Chordoma: current concepts, management, and future directions

BP Walcott, BV Nahed, A Mohyeldin… - The lancet …, 2012 - thelancet.com
Chordoma is a rare bone cancer that is aggressive, locally invasive, and has a poor
prognosis. Chordomas are thought to arise from transformed remnants of notochord and …

Chordoma—current understanding and modern treatment paradigms

SM Barber, SS Sadrameli, JJ Lee, JS Fridley… - Journal of clinical …, 2021 - mdpi.com
Chordoma is a low-grade notochordal tumor of the skull base, mobile spine and sacrum
which behaves malignantly and confers a poor prognosis despite indolent growth patterns …

En bloc resection of primary sacral tumors: classification of surgical approaches and outcome

DR Fourney, LD Rhines, SJ Hentschel… - … of Neurosurgery: Spine, 2005 - thejns.org
Object En bloc resection with adequate margins is associated with the highest probability of
long-term tumor control or cure in most cases of primary sacral malignancies. The authors …

Tumors of the retrorectal space

KG Hobson, V Ghaemmaghami, JP Roe… - Diseases of the colon …, 2005 - journals.lww.com
PURPOSE: Retrorectal tumors are a diverse group of masses derived from a variety of
embryologic origins. Because of this, some confusion is associated with their diagnosis and …

Long-term clinical outcomes following en bloc resections for sacral chordomas and chondrosarcomas: a series of twenty consecutive patients

PC Hsieh, R Xu, DM Sciubba, MJ McGirt, C Nelson… - Spine, 2009 - journals.lww.com
Study Design. Retrospective study of 20 consecutive patients who underwent en bloc tumor
excision of sacral chordomas and chondrosarcomas. Objective. To evaluate the functional …

Thirty-day readmission and reoperation after surgery for spinal tumors: a National Surgical Quality Improvement Program analysis

AV Karhade, VS Vasudeva, HH Dasenbrock, Y Lu… - Neurosurgical …, 2016 - thejns.org
OBJECTIVE The goal of this study was to use a large national registry to evaluate the 30-day
cumulative incidence and predictors of adverse events, readmissions, and reoperations after …

Feasibility and safety of en bloc resection for primary spine tumors: a systematic review by the Spine Oncology Study Group

T Yamazaki, GS McLoughlin, S Patel, LD Rhines… - Spine, 2009 - journals.lww.com
Study Design. Systematic review. Objectives. To determine the general feasibility and safety
of en bloc resection for primary spine tumors by analyzing (1) the effect of incisional biopsy …

Surgical treatment of sacral chordoma: prognostic variables for local recurrence and overall survival

PP Varga, Z Szövérfi, CG Fisher, S Boriani… - European Spine …, 2015 - Springer
Purpose Sacral chordomas (SC) are rare, locally invasive, malignant neoplasms. Despite
surgical resection and adjuvant therapies, local recurrence (LR) is common and overall …

Posterior-only approach for en bloc sacrectomy: clinical outcomes in 36 consecutive patients

MJ Clarke, H Dasenbrock, A Bydon, DM Sciubba… - …, 2012 - journals.lww.com
BACKGROUND: En bloc resection of primary sacral tumors has a demonstrated survival
benefit. Total and high sacral amputations are traditionally performed by using a staged …

A review of the surgical management of sacral chordoma

B Kayani, SA Hanna, MD Sewell, A Saifuddin… - European Journal of …, 2014 - Elsevier
Background Sacral chordomas are rare low-to-intermediate grade malignant tumours, which
arise from remnants of the embryonic notochord. This review explores prognostic factors in …