Trained innate immunity as underlying mechanism for the long-term, nonspecific effects of vaccines

BA Blok, RJW Arts, R van Crevel… - Journal of Leucocyte …, 2015 - academic.oup.com
An increasing body of evidence shows that the innate immune system has adaptive
characteristics that involve a heterologous memory of past insults. Both experimental models …

Yellow fever control: current epidemiology and vaccination strategies

LH Chen, ME Wilson - Tropical diseases, travel medicine and vaccines, 2020 - Springer
Yellow fever (YF) outbreaks continue, have expanded into new areas and threaten large
populations in South America and Africa. Predicting where epidemics might occur must take …

Fractional Doses of Pneumococcal Conjugate Vaccine—A Noninferiority Trial

KE Gallagher, R Lucinde, C Bottomley… - … England Journal of …, 2024 - Mass Medical Soc
Background Pneumococcal conjugate vaccines are an expensive component of the routine
immunization schedule. Fractional-dose regimens may be one option to increase the …

Emerging and Reemerging Aedes-Transmitted Arbovirus Infections in the Region of the Americas: Implications for Health Policy

MA Espinal, JK Andrus, B Jauregui… - … journal of public …, 2019 - ajph.aphapublications.org
The increasing geographical spread and disease incidence of arboviral infections are
among the greatest public health concerns in the Americas. The region has observed an …

Progress and works in progress: update on flavivirus vaccine development

MH Collins, SW Metz - Clinical therapeutics, 2017 - Elsevier
Most areas of the globe are endemic for at least one flavivirus, putting billions at risk for
infection. This diverse group of viral pathogens causes a range of manifestations in humans …

Duration of protection after vaccination against yellow fever: a systematic review and meta-analysis

K Kling, C Domingo, C Bogdan, S Duffy… - Clinical Infectious …, 2022 - academic.oup.com
The duration of protection after a single dose of yellow fever vaccine is a matter of debate.
To summarize the current knowledge, we performed a systematic literature review and meta …

The present and future of yellow fever vaccines

CA Hansen, ADT Barrett - Pharmaceuticals, 2021 - mdpi.com
The disease yellow fever (YF) is prevented by a live-attenuated vaccine, termed 17D, which
has been in use since the 1930s. One dose of the vaccine is thought to give lifelong (35+ …

Immunogenicity of fractional-dose vaccine during a yellow fever outbreak

RM Casey, JB Harris, S Ahuka-Mundeke… - … England Journal of …, 2019 - Mass Medical Soc
Background In 2016, the response to a yellow fever outbreak in Angola and the Democratic
Republic of Congo led to a global shortage of yellow fever vaccine. As a result, a fractional …

Live attenuated yellow fever 17D vaccine: a legacy vaccine still controlling outbreaks in modern day

ND Collins, ADT Barrett - Current infectious disease reports, 2017 - Springer
Abstract Purpose of Review Live attenuated 17D vaccine is considered one of the safest and
efficacious vaccines developed to date. This review highlights what is known and the gaps …

Yellow fever live attenuated vaccine: A very successful live attenuated vaccine but still we have problems controlling the disease

ADT Barrett - Vaccine, 2017 - Elsevier
Yellow fever (YF) is regarded as the original hemorrhagic fever and has been a major public
health problem for at least 250 years. A very effective live attenuated vaccine, strain 17D …