Effects and mechanisms of phthalates' action on reproductive processes and reproductive health: a literature review

H Hlisníková, I Petrovičová, B Kolena… - International journal of …, 2020 - mdpi.com
The production of plastic products, which requires phthalate plasticizers, has resulted in the
problems for human health, especially that of reproductive health. Phthalate exposure can …

Exposure to phthalates and female reproductive health: A literature review

CG Basso, AT de Araújo-Ramos… - Reproductive …, 2022 - Elsevier
Endocrine-disrupting chemicals (EDCs) are exogenous compounds that have been known
for their ability to interfere with the action of hormones and affect endocrine pathways …

Multi-step processing of replication stress-derived nascent strand DNA gaps by MRE11 and EXO1 nucleases

A Hale, A Dhoonmoon, J Straka, CM Nicolae… - Nature …, 2023 - nature.com
Accumulation of single stranded DNA (ssDNA) gaps in the nascent strand during DNA
replication has been associated with cytotoxicity and hypersensitivity to genotoxic stress …

Functionalized UIO-66@ Ag nanoparticles substrate for rapid and ultrasensitive SERS detection of di-(2-ethylhexyl) phthalate in plastics

H Xu, J Zhu, Y Cheng, D Cai - Sensors and Actuators B: Chemical, 2021 - Elsevier
The rapid and sensitive detection of di-(2-ethylhexyl) phthalate (DEHP) in plastics is of great
significance because of its toxicity and persistent contamination. Surface-enhanced Raman …

Effects of phthalate mixtures on ovarian folliculogenesis and steroidogenesis

EJ Fletcher, R Santacruz-Márquez, VE Mourikes… - Toxics, 2022 - mdpi.com
The female reproductive system is dependent upon the health of the ovaries. The ovaries
are responsible for regulating reproduction and endocrine function. Throughout a female's …

[HTML][HTML] Di (2-ethylhexyl) phthalate-induced reproductive toxicity involved in DNA damage-dependent oocyte apoptosis and oxidative stress in Caenorhabditis …

J Yin, R Liu, Z Jian, D Yang, Y Pu, L Yin… - … and environmental safety, 2018 - Elsevier
Abstract Di-(2-ethylhexyl) phthalate (DEHP) is a widely used plasticizer with a high
environmental exposure level. As a persistent organic pollutant, DEHP causes reproductive …

DEHP exposure to lactating mice affects ovarian hormone production and antral follicle development of offspring

JC Liu, CH Xing, Y Xu, ZN Pan, HL Zhang… - Journal of hazardous …, 2021 - Elsevier
Abstract Di (2-ethylhexyl) phthalate (DEHP) is widely used as a plastic additive and it could
induce reproduction defects and fertility in mammals as environmental endocrine disruptor …

Di-(2-ethylhexyl) phthalate induced developmental abnormalities of the ovary in quail (Coturnix japonica) via disruption of the hypothalamic-pituitary-ovarian axis

XN Li, HX Li, TN Yang, XW Li, YQ Huang… - Science of The Total …, 2020 - Elsevier
An increasing number of epidemiologic studies show that women have a special exposure
profile to phthalates, and the exposures have attracted attention regarding their potential …

[HTML][HTML] Single-cell transcriptome dissection of the toxic impact of Di (2-ethylhexyl) phthalate on primordial follicle assembly

JJ Wang, Y Tian, MH Li, YQ Feng, L Kong, FL Zhang… - Theranostics, 2021 - ncbi.nlm.nih.gov
Rationale: Accumulated evidence indicates that environmental plasticizers are a threat to
human and animal fertility. Di (2-ethylhexyl) phthalate (DEHP), a plasticizer to which humans …

[HTML][HTML] Exposure to Di-(2-Ethylhexyl) phthalate drives ovarian dysfunction by inducing granulosa cell pyroptosis via the SLC39A5/NF-κB/NLRP3 axis

J Sun, L Gan, S Lv, T Wang, C Dai, J Sun - … and Environmental Safety, 2023 - Elsevier
Endocrine-disrupting chemicals (EDCs) have been reported to affect populations by
disrupting the human endocrine system. Di-(2-ethylhexyl) phthalate (DEHP) is an EDC that …