The neuroinvasiveness, neurotropism, and neurovirulence of SARS-CoV-2

L Bauer, BM Laksono, FMS de Vrij, SA Kushner… - Trends in …, 2022 - cell.com
Severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) infection is associated with
a diverse spectrum of neurological complications during the acute and postacute stages …

Challenges of organoid research

MG Andrews, AR Kriegstein - Annual review of neuroscience, 2022 - annualreviews.org
Organoids are 3D cell culture systems derived from human pluripotent stem cells that
contain tissue resident cell types and reflect features of early tissue organization. Neural …

[HTML][HTML] Outpatient treatment of COVID-19 and incidence of post-COVID-19 condition over 10 months (COVID-OUT): a multicentre, randomised, quadruple-blind …

CT Bramante, JB Buse, DM Liebovitz… - The Lancet Infectious …, 2023 - thelancet.com
Summary Background Post-COVID-19 condition (also known as long COVID) is an
emerging chronic illness potentially affecting millions of people. We aimed to evaluate …

[HTML][HTML] Neuroinvasion and anosmia are independent phenomena upon infection with SARS-CoV-2 and its variants

GD de Melo, V Perraud, F Alvarez… - Nature …, 2023 - nature.com
Anosmia was identified as a hallmark of COVID-19 early in the pandemic, however, with the
emergence of variants of concern, the clinical profile induced by SARS-CoV-2 infection has …

[HTML][HTML] Impact of age and sex on antibody response following the second dose of COVID-19 BNT162b2 mRNA vaccine in Greek healthcare workers

N Vassilaki, AN Gargalionis, A Bletsa… - Microorganisms, 2021 - mdpi.com
Anti-SARS-CoV-2 spike RBD (receptor-binding domain) IgG antibody levels were monitored
in 1643 volunteer healthcare workers of Eginition, Evangelismos, and Konstantopoulio …

[HTML][HTML] Metformin for treatment of acute COVID-19: systematic review of clinical trial data against SARS-CoV-2

SM Erickson, SL Fenno, N Barzilai, G Kuchel… - Diabetes …, 2023 - Am Diabetes Assoc
BACKGROUND Observational and preclinical data suggest metformin may prevent severe
coronavirus disease 2019 (COVID-19) outcomes. PURPOSE We conducted a systematic …

[HTML][HTML] Outpatient treatment of Covid-19 with metformin, ivermectin, and fluvoxamine and the development of Long Covid over 10-month follow-up

CT Bramante, JB Buse, D Liebovitz, J Nicklas… - medRxiv, 2022 - ncbi.nlm.nih.gov
Background Long Covid is an emerging chronic illness potentially affecting millions,
sometimes preventing the ability to work or participate in normal daily activities. COVID-OUT …

[HTML][HTML] Can SARS-CoV-2 infection lead to neurodegeneration and Parkinson's disease?

L Krey, MK Huber, GU Höglinger, F Wegner - Brain Sciences, 2021 - mdpi.com
The SARS-CoV-2 pandemic has affected the daily life of the worldwide population since
2020. Links between the newly discovered viral infection and the pathogenesis of …

[HTML][HTML] The relationship between chronic immune response and neurodegenerative damage in long COVID-19

JP Elizalde-Díaz, CL Miranda-Narváez… - Frontiers in …, 2022 - frontiersin.org
In the past two years, the world has faced the pandemic caused by the severe acute
respiratory syndrome 2 coronavirus (SARS-CoV-2), which by August of 2022 has infected …

[HTML][HTML] Cellular and molecular effects of SARS-CoV-2 linking lung infection to the brain

L Francistiova, A Klepe, G Curley, K Gulya… - Frontiers in …, 2021 - frontiersin.org
In December 2019, a new viral disease emerged and quickly spread all around the world. In
March 2020, the COVID-19 outbreak was classified as a global pandemic and by June …