Chitosan: A review on properties, biological activities and recent progress in biomedical applications

A Harugade, AP Sherje, A Pethe - Reactive and Functional Polymers, 2023 - Elsevier
Chitosan is a naturally occurring amino polysaccharide obtained by deacetylation of chitin
and is second most commonly used natural polymer. Its non-toxic, biocompatibility and …

Competitive biological activities of chitosan and its derivatives: Antimicrobial, antioxidant, anticancer, and anti‐inflammatory activities

S Kim - International journal of polymer science, 2018 - Wiley Online Library
Chitosan is obtained from alkaline deacetylation of chitin, and acetamide groups are
transformed into primary amino groups during the deacetylation. The diverse biological …

Chitosan as excellent bio-macromolecule with myriad of anti-activities in biomedical applications–A review

S Jagdale, B Agarwal, A Dixit, S Gaware - International Journal of …, 2024 - Elsevier
The aim of the study is to explore the myriad of anti-activities of chitosan-deacylated
derivative of chitin in biomedical applications. Chitosan consists of reactive residual amino …

Amelioration of cancer employing chitosan, its derivatives, and chitosan-based nanoparticles: recent updates

T Virmani, G Kumar, A Sharma, K Pathak, MS Akhtar… - Polymers, 2023 - mdpi.com
The limitations associated with the conventional treatment of cancer have necessitated the
design and development of novel drug delivery systems based mainly on nanotechnology …

Chitosan-based advanced materials for docetaxel and paclitaxel delivery: Recent advances and future directions in cancer theranostics

M Ashrafizadeh, Z Ahmadi, N Mohamadi… - International journal of …, 2020 - Elsevier
Paclitaxel (PTX) and docetaxel (DTX) are key members of taxanes with high anti-tumor
activity against various cancer cells. These chemotherapeutic agents suffer from a number of …

Chitosan-based smart stimuli-responsive nanoparticles for gene delivery and gene therapy: Recent progresses on cancer therapy

SM Naghib, B Ahmadi, BM Kangarshahi… - International Journal of …, 2024 - Elsevier
Recent cancer therapy research has found that chitosan (Ch)-based nanoparticles show
great potential for targeted gene delivery. Chitosan, a biocompatible and biodegradable …

Fe3O4 nanoparticles coated with carboxymethyl chitosan containing curcumin in combination with hyperthermia induced apoptosis in breast cancer cells

N Pazouki, S Irani, N Olov, SM Atyabi… - Progress in …, 2022 - Springer
Many studies have demonstrated that curcumin has potential anticancer properties. This
research aims to study the effect of iron (II, III) oxide (Fe3O4) nanoparticles coated with …

Polymeric nanoparticles: Exploring the current drug development and therapeutic insight of breast cancer treatment and recommendations

A Sartaj, Z Qamar, FF Qizilbash, Annu, S Md… - Polymers, 2021 - mdpi.com
This manuscript aims to provide the latest update on polymeric nanoparticle drug delivery
system for breast cancer treatment after 2015 and how research-oriented it is based on the …

Actively targeted and redox responsive delivery of anticancer drug by chitosan nanoparticles

E Mazzotta, S De Benedittis, A Qualtieri, R Muzzalupo - Pharmaceutics, 2019 - mdpi.com
The clinical efficacy of methotrexate (MTX) is limited by its poor water solubility, its low
bioavailability, and the development of resistance in cancer cells. Herein, we developed …

Plausible role of chitosan in drug and gene delivery against resistant breast cancer cells

T Nandgude, R Pagar - Carbohydrate Research, 2021 - Elsevier
Breast cancer is the highest global spread of invasive cancer in women. While significant
progress has been made in breast cancer, diagnostic and therapeutic effective prevention …