New insights into the T cell synapse from single molecule techniques

ML Dustin, D Depoil - Nature Reviews Immunology, 2011 - nature.com
T cell activation depends on extracellular ligation of the T cell receptor (TCR) by peptide–
MHC complexes in a synapse between the T cell and an antigen-presenting cell. The …

Simulation tools for particle-based reaction-diffusion dynamics in continuous space

J Schöneberg, A Ullrich, F Noé - BMC biophysics, 2014 - Springer
Particle-based reaction-diffusion algorithms facilitate the modeling of the diffusional motion
of individual molecules and the reactions between them in cellular environments. A …

Electrochemical impedance spectroscopy of tethered bilayer membranes

G Valincius, T Meškauskas, F Ivanauskas - Langmuir, 2012 - ACS Publications
The electrochemical impedance spectra (EIS) of tethered bilayer membranes (tBLMs) were
analyzed, and the analytical solution for the spectral response of membranes containing …

Dynamical organization of syntaxin-1A at the presynaptic active zone

A Ullrich, MA Böhme, J Schöneberg… - PLoS computational …, 2015 - journals.plos.org
Synaptic vesicle fusion is mediated by SNARE proteins forming in between synaptic vesicle
(v-SNARE) and plasma membrane (t-SNARE), one of which is Syntaxin-1A. Although …

Cluster formation in fluids with competing short-range and long-range interactions

MB Sweatman, R Fartaria, L Lue - The Journal of chemical physics, 2014 - pubs.aip.org
We investigate the low density behaviour of fluids that interact through a short-ranged
attraction together with a long-ranged repulsion (SALR potential) by developing a molecular …

Molecular dynamics investigation of clustering in aqueous glycine solutions

MB Sweatman, ND Afify… - The Journal of …, 2022 - ACS Publications
Recent experiments with undersaturated aqueous glycine solutions have repeatedly
exhibited the presence of giant liquid-like clusters or nanodroplets around 100 nm in …

The extracellular δ-domain is essential for the formation of CD81 tetraspanin webs

Y Homsi, JG Schloetel, KD Scheffer, TH Schmidt… - Biophysical journal, 2014 - cell.com
CD81 is a ubiquitously expressed member of the tetraspanin family. It forms large molecular
platforms, so-called tetraspanin webs that play physiological roles in a variety of cellular …

Membrane microdomains: from seeing to understanding

BA Truong-Quang, PF Lenne - Frontiers in plant science, 2014 - frontiersin.org
The plasma membrane is a composite material, which forms a semi-permeable barrier and
an interface for communication between the intracellular and extracellular environments …

[HTML][HTML] Distribution and dynamics of OXPHOS complexes in the bacterial cytoplasmic membrane

A Magalon, F Alberge - Biochimica et Biophysica Acta (BBA)-Bioenergetics, 2016 - Elsevier
Oxidative phosphorylation (OXPHOS) is an essential process for most living organisms
mostly sustained by protein complexes embedded in the cell membrane. In order to thrive …

Role of the membrane anchor in the regulation of Lck activity

N Porciello, D Cipria, G Masi, AL Lanz… - Journal of Biological …, 2022 - ASBMB
Theoretical work suggests that collective spatiotemporal behavior of integral membrane
proteins should be modulated by boundary lipids sheathing their membrane anchors. Here …