Osteoconductive and osteoinductive surface modifications of biomaterials for bone regeneration: A concise review

P Kazimierczak, A Przekora - Coatings, 2020 - mdpi.com
The main aim of bone tissue engineering is to fabricate highly biocompatible,
osteoconductive and/or osteoinductive biomaterials for tissue regeneration. Bone implants …

[HTML][HTML] Zinc based biodegradable metals for bone repair and regeneration: Bioactivity and molecular mechanisms

P Li, J Dai, Y Li, D Alexander, J Čapek… - Materials Today Bio, 2024 - Elsevier
Bone fractures and critical-size bone defects are significant public health issues, and clinical
treatment outcomes are closely related to the intrinsic properties of the utilized implant …

[HTML][HTML] 3D-Printed PCL/Zn scaffolds for bone regeneration with a dose-dependent effect on osteogenesis and osteoclastogenesis

S Wang, R Gu, F Wang, X Zhao, F Yang, Y Xu, F Yan… - Materials Today Bio, 2022 - Elsevier
Polycaprolactone (PCL) is a polymer material suitable for being prepared into porous
scaffolds used in bone tissue engineering, however, insufficient osteogenic ability and …

The incorporation of zinc into hydroxyapatite and its influence on the cellular response to biomaterials: a systematic review

J Dornelas, G Dornelas, A Rossi, A Piattelli… - Journal of Functional …, 2024 - mdpi.com
Zinc is known for its role in enhancing bone metabolism, cell proliferation, and tissue
regeneration. Several studies proposed the incorporation of zinc into hydroxyapatite (HA) to …

Metal ions: The unfading stars of bone regeneration—From bone metabolism regulation to biomaterial applications

Y Luo, H Liu, Y Zhang, Y Liu, S Liu, X Liu… - Biomaterials Science, 2023 - pubs.rsc.org
In recent years, bone regeneration has emerged as a remarkable field that offers promising
guidance for treating bone-related diseases, such as bone defects, bone infections, and …

A critical review of biodegradable zinc alloys toward clinical applications

J Rao, H Gao, J Sun, R Yu, D Zhao… - … Biomaterials Science & …, 2024 - ACS Publications
Biodegradable zinc (Zn) alloys stand out as promising contenders for biomedical
applications due to their favorable mechanical properties and appropriate degradation rates …

Metal-organic Zn-zoledronic acid and 1-hydroxyethylidene-1, 1-diphosphonic acid nanostick-mediated zinc phosphate hybrid coating on biodegradable Zn for …

J Qian, H Qin, P Zeng, J Hou, X Mo, G Shen, H Zeng… - Acta Biomaterialia, 2023 - Elsevier
Zn and its alloys are increasingly under consideration for biodegradable bone fracture
fixation implants owing to their attractive biodegradability and mechanical properties …

Hydroxyapatite or fluorapatite—which bioceramic is better as a base for the production of bone scaffold?—A comprehensive comparative study

P Kazimierczak, J Wessely-Szponder, K Palka… - International Journal of …, 2023 - mdpi.com
Hydroxyapatite (HAP) is the most common calcium phosphate ceramic that is used in
biomedical applications, eg, as an inorganic component of bone scaffolds. Nevertheless …

[HTML][HTML] Angiogenesis-osteogenesis coupling and anti-osteoclastogenesis zoledronate intermixed calcium silicate metal-organic/inorganic hybrid coating on …

J Qian, H Qin, E Su, J Hou, H Zeng, T Wang, D Wang… - Bioactive Materials, 2025 - Elsevier
Osteoporotic (OP) fractures remain a tough clinical challenge owing to their impaired
healing outcome, which requires novel biomaterials with osteogenicity for effective healing …

The role of zinc in bone mesenchymal stem cell differentiation

H Li, M Li, X Ran, J Cui, F Wei, G Yi, W Chen… - Cellular …, 2022 - liebertpub.com
Zinc is an essential trace element for bone growth and bone homeostasis in the human
body. Bone mesenchymal stem cells (BMSCs) are multipotent progenitors existing in the …