Kidney disease, especially when it is associated with a reduction in estimated glomerular
filtration rate, can be associated with an increase in serum urate (uric acid), suggesting that …

Abstract Purpose of the Review Our review explores the epidemiology, physiology, and
clinical data surrounding the connection between hyperuricemia and metabolic syndrome …

Germline mutations in cellular-energy associated genes have been shown to lead to various
monogenic disorders. Notably, mitochondrial disorders often impact skeletal muscle, brain …

The loss of cognitive function in Alzheimer's disease is pathologically linked with
neurofibrillary tangles, amyloid deposition, and loss of neuronal communication. Cerebral …

Intradialytic hypotension (IDH) is a serious complication of hemodialysis (HD), with an
incidence of more than 20%. IDH induces ischemic organ damage and even reduces the …

Objectives The aim of this study was to elucidate the impact of nutritional status on survival
per Controlling Nutritional Status (CONUT) score and Geriatric Nutritional Risk Index (GNRI) …

Background Conflicting results have been reported from studies evaluating serum uric acid
(SUA) levels as an independent risk factor for cardiovascular mortality in patients with …

Background The association between serum uric acid (SUA) and mortality has been
conflicting among studies using hemodialysis (HD) patients. Given the close link between …

Background Serum uric acid (SUA) has been demonstrated as a risk factor for myocardial
infarction (MI) and all‐cause mortality; however, the impact of cumulative SUA (cumSUA) …

Uric acid‐mediated biological effects are milieu dependent. In a physiological milieu, serum
uric acid serves as an antioxidant; when homeostasis is perturbed, divergent effects are …