Metabolomics and type 2 diabetes risk: an updated systematic review and meta-analysis of prospective cohort studies

J Morze, C Wittenbecher, L Schwingshackl… - Diabetes …, 2022 - Am Diabetes Assoc
BACKGROUND Due to the rapidly increasing availability of metabolomics data in
prospective studies, an update of the meta evidence on metabolomics and type 2 diabetes …

Metabolomics signatures in type 2 diabetes: a systematic review and integrative analysis

Y Sun, HY Gao, ZY Fan, Y He… - The Journal of Clinical …, 2020 - academic.oup.com
Objective Metabolic signatures have emerged as valuable signaling molecules in the
biochemical process of type 2 diabetes (T2D). To summarize and identify metabolic …

Imidazole propionate is increased in diabetes and associated with dietary patterns and altered microbial ecology

A Molinaro, P Bel Lassen, M Henricsson, H Wu… - Nature …, 2020 - nature.com
Microbiota-host-diet interactions contribute to the development of metabolic diseases.
Imidazole propionate is a novel microbially produced metabolite from histidine, which …

Targeting BCAA catabolism to treat obesity-associated insulin resistance

M Zhou, J Shao, CY Wu, L Shu, W Dong, Y Liu… - Diabetes, 2019 - Am Diabetes Assoc
Recent studies implicate a strong association between elevated plasma branched-chain
amino acids (BCAAs) and insulin resistance (IR). However, a causal relationship and …

Diabetes and branched-chain amino acids: What is the link?

Z Bloomgarden - Journal of diabetes, 2018 - europepmc.org
Branched-chain amino acids (BCAA) have increasingly been studied as playing a role in
diabetes, with the PubMed search string" diabetes" AND" branched chain amino acids" …

Unveiling the future of metabolic medicine: omics technologies driving personalized solutions for precision treatment of metabolic disorders

S Singh, DK Sarma, V Verma, R Nagpal… - … and Biophysical Research …, 2023 - Elsevier
Metabolic disorders are increasingly prevalent worldwide, leading to high rates of morbidity
and mortality. The variety of metabolic illnesses can be addressed through personalized …

[HTML][HTML] Maternal obesity and the human milk metabolome: associations with infant body composition and postnatal weight gain

E Isganaitis, S Venditti, TJ Matthews, C Lerin… - The American journal of …, 2019 - Elsevier
Background Maternal obesity is a risk factor for childhood obesity; this is a major public
health concern given that∼ 40% of pregnant women are either overweight or obese …

Metabolomic analysis of obesity, metabolic syndrome, and type 2 diabetes: amino acid and acylcarnitine levels change along a spectrum of metabolic wellness

DM Libert, AS Nowacki, MR Natowicz - PeerJ, 2018 - peerj.com
Background Metabolic syndrome (MS) is a construct used to separate “healthy” from
“unhealthy” obese patients, and is a major risk factor for type 2 diabetes (T2D) and …

Metabolic signatures and risk of type 2 diabetes in a Chinese population: an untargeted metabolomics study using both LC-MS and GC-MS

Y Lu, Y Wang, CN Ong, T Subramaniam, HW Choi… - Diabetologia, 2016 - Springer
Aims/hypothesis Metabolomics has provided new insight into diabetes risk assessment. In
this study we characterised the human serum metabolic profiles of participants in the …

The Consortium of Metabolomics Studies (COMETS): metabolomics in 47 prospective cohort studies

B Yu, KA Zanetti, M Temprosa… - American journal of …, 2019 - academic.oup.com
Abstract The Consortium of Metabolomics Studies (COMETS) was established in 2014 to
facilitate large-scale collaborative research on the human metabolome and its relationship …