Yang and co-workers appeared (Figure 1), 2 and 16 years since their accompanying
Accounts article,“Chemical Detoxification of Nerve Agent VX.” 14 Also, organophosphonate …

Epilepsy is a common neurological disorder characterized by an initial injury due to stroke,
traumatic brain injury, brain infection, or febrile seizures causing status epilepticus (SE). This …

The translational capacity of data generated in preclinical toxicological studies is contingent
upon several factors, including the appropriateness of the animal model. The primary …

Sarin (GB, O-isopropyl methylphosphonofluoridate) is a potent organophosphorus (OP)
nerve agent that inhibits acetylcholinesterase (AChE) irreversibly. The subsequent build-up …

The lithium‐pilocarpine model is a rat model of epilepsy that mimics status epilepticus in
humans. Here, we report changes of acetylcholine (ACh) release in the hippocampus …

To understand better the cerebral functions, several methods have been developed to study
the brain activity, they could be related with morphological, electrophysiological, molecular …

Encephalitic alphaviruses (EEVs), Traumatic Brain Injuries (TBI), and organophosphorus
nerve agents (NAs) are three diverse biological, physical, and chemical injuries that can …

Organophosphorus nerve agents such as soman (GD) inhibit acetylcholinesterase,
producing an excess of acetylcholine (ACh), which results in respiratory distress …

Some organophosphorus compounds (OPs) are nerve agents that continue to concern
military personnel and civilians as potential battlefield and terrorist threats. Additionally, OPs …

The current regimen for treating nerve agent poisoning does not sufficiently suppress the
excitotoxic activity that causes severe brain damage, especially in cases where treatment is …