HPV-associated oropharyngeal cancer: epidemiology, molecular biology and clinical management

M Lechner, J Liu, L Masterson, TR Fenton - Nature reviews Clinical …, 2022 - nature.com
Abstract Human papillomavirus (HPV)-positive (HPV+) oropharyngeal squamous cell
carcinoma (OPSCC) has one of the most rapidly increasing incidences of any cancer in high …

Human papillomaviruses: diversity, infection and host interactions

AA McBride - Nature Reviews Microbiology, 2022 - nature.com
Human papillomaviruses (HPVs) are an ancient and highly successful group of viruses that
have co-evolved with their host to replicate in specific anatomical niches of the stratified …

Cervical cancer immunotherapy: facts and hopes

L Ferrall, KY Lin, RBS Roden, CF Hung, TC Wu - Clinical Cancer Research, 2021 - AACR
It is a sad fact that despite being almost completely preventable through human
papillomavirus (HPV) vaccination and screening, cervical cancer remains the fourth most …

The immunological anatomy of the skin

K Kabashima, T Honda, F Ginhoux… - Nature Reviews …, 2019 - nature.com
The skin is the outermost organ of the body and is continuously exposed to external
pathogens. Upon inflammation, various immune cells pass through, reside in or are …

The natural history of human papillomavirus infection

S de Sanjose, M Brotons, MA Pavon - Best practice & research Clinical …, 2018 - Elsevier
Human papillomavirus (HPV) is a small double-stranded DNA virus that commonly infects
humans. The oncogenic characteristics of HPV derive from the oncoproteins E6 and E7 that …

Carcinogenic human papillomavirus infection

M Schiffman, J Doorbar, N Wentzensen… - Nature reviews Disease …, 2016 - nature.com
Infections with human papillomavirus (HPV) are common and transmitted by direct contact.
Although the great majority of infections resolve within 2 years, 13 phylogenetically related …

HPV post-infection microenvironment and cervical cancer

Y Yuan, X Cai, F Shen, F Ma - Cancer Letters, 2021 - Elsevier
Human papillomavirus (HPV) is the most common sexually transmitted virus worldwide.
More than 99% of cervical cancer cases are associated with certain types of HPVs, termed …

The human papillomavirus replication cycle, and its links to cancer progression: a comprehensive review

SV Graham - Clinical science, 2017 - portlandpress.com
HPVs (human papillomaviruses) infect epithelial cells and their replication cycle is intimately
linked to epithelial differentiation. There are over 200 different HPV genotypes identified to …

Persistent human papillomavirus infection

AN Della Fera, A Warburton, TL Coursey, S Khurana… - Viruses, 2021 - mdpi.com
Simple Summary The success of HPV as an infectious agent lies not within its ability to
cause disease, but rather in the adeptness of the virus to establish long-term persistent …

Mucosal and cutaneous human papillomavirus infections and cancer biology

T Gheit - Frontiers in Oncology, 2019 - frontiersin.org
Papillomaviridae is a family of small non-enveloped icosahedral viruses with double-
stranded circular DNA. More than 200 different human papillomaviruses (HPVs) have been …