The advent of immunotherapy has marked a new era in cancer treatment, offering significant
clinical benefits. Cell membrane as drug delivery materials has played a crucial role in …

RNA-based therapies, and siRNAs in particular, have attractive therapeutic potential for
cancer treatment due to their ability to silence genes that are imperative for tumor …

Pulmonary fibrosis (PF) is a progressive, and life-threatening interstitial lung disease which
causes scarring in the lung parenchyma and thereby affects architecture and functioning of …

The use of cellular nanovesicles (CNVs) is a groundbreaking innovation in biomedical
applications. Both natural extracellular vesicles (EVs) and artificial cell membrane …

Gene therapy is a promising therapeutic approach to treating different diseases; however,
the lack of platforms that can safely and efficiently carry desired genes to the targeted …

Oligonucleotide gene therapy (OGT) agents (eg antisense, deoxyribozymes, siRNA and
CRISPR/Cas) are promising therapeutic tools. Despite extensive efforts, only few OGT drugs …

Nonviral nanoparticles have emerged as an attractive alternative to viral vectors for gene
therapy applications, utilizing a range of lipid‐based, polymeric, and inorganic materials …

Autografting, a major treatment for bone fractures, has potential risks related to the required
surgery and disease transmission. Bone morphogenetic proteins (BMPs) are the most …

Background Genomic safe harbors are regions of the genome that can maintain transgene
expression without disrupting the function of host cells. Genomic safe harbors play an …

Gene therapy has emerged as a significant advancement in medicine in recent years.
However, the development of effective gene delivery vectors, particularly polymer vectors …