Neurons in most animals live a very long time relative to the half-lives of all of the proteins
that govern excitability and synaptic transmission. Consequently, homeostatic mechanisms …

Homeostasis is a specialized form of regulation that precisely maintains the function of a
system at a set point level of activity. Recently, homeostatic signaling has been suggested to …

It is often assumed that cellular and synaptic properties need to be regulated to specific
values to allow a neuronal network to function properly. To determine how tightly neuronal …

The brain is astonishing in its complexity and capacity for change. This has fascinated
scientists for more than a century, filling the pages of this journal for the past 25 years. But a …

Here we describe the properties of a synapse in the Drosophila antennal lobe and show
how they can explain certain sensory computations in this brain region. The synapse …

Which features of network output are well preserved during growth of the nervous system
and across different preparations of the same size? To address this issue, we characterized …

The output of a neural circuit results from an interaction between the intrinsic properties of
neurons in the circuit and the features of the synaptic connections between them. The …

In many species, excitable cells preserve their physiological properties despite significant
variation in physical size across time and in a population. For example, neurons in …

Recent experimental and modeling results demonstrated that surviving mossy cells in the
dentate gyrus play key roles in the generation of network hyperexcitability. Here we …

Neurons–Glia–Synapses–General layout of the central nervous system–Architecture of the
brain–The ventral nerve cord–Motor systems. Non–Malacostraca–Remipedia …