Deep learning (DL) can accelerate the prediction of prognostic biomarkers from routine
pathology slides in colorectal cancer (CRC). However, current approaches rely on …

Inflammatory bowel disease (IBD) has been referred to as the “green cancer,” and its
progression to colorectal cancer (CRC) poses a significant challenge for the medical …

Methods To determine whether blockade of MCT4 alone is sufficient to improve the efficacy
of immune checkpoint blockade (ICB) therapy, we examined the effects of the selective …

Heightened lactate production in cancer cells has been linked to various cellular
mechanisms such as angiogenesis, hypoxia, macrophage polarisation and T‐cell …

Abstract Background Stroma AReactive Invasion Front Areas (SARIFA) is a recently
identified haematoxylin & eosin (H&E) based histopathologic biomarker in gastrointestinal …

Early‐life (childhood to adolescence) energy balance‐related factors (height, energy
restriction, BMI) have been associated with adult colorectal cancer (CRC) risk. Warburg …

Purpose Tumor location and tumor node metastasis (TNM) stage guide treatment decisions
in colorectal cancer (CRC) patients. However, patients with the same disease stage do not …

Background Previous research suggests that Warburg‐subtypes are related to potentially
important survival differences in colorectal cancer (CRC) patients. In the present study, we …

Colorectal cancer (CRC) remains one of the most prevalent and deadly cancers worldwide.
The tumour-node-metastasis stage (TNM) is currently the most clinically important tool to …

Over the past years, insights in the cancer neuroscience field increased rapidly, and a
potential role for neurons in colorectal carcinogenesis has been recognized. However …