The imbalance between glutamate and γ‐aminobutyric acid (GABA) results in the loss of
synaptic strength leading to neurodegeneration. The dogma on the field considered neurons …

The pathological role of reactive gliosis in CNS repair remains controversial. In this study,
using murine ischemic and hemorrhagic stroke models, we demonstrated that microglia …

Dissecting the functional roles of neuronal circuits and their interaction is a crucial step in
basic neuroscience and in all the biomedical field. Optogenetics is well-suited to this …

Transcranial focused ultrasound stimulation (tFUS) regulates neural activity in different brain
regions in humans and animals. However, the role of ultrasound stimulation in modulating …

Stroke is the most common cause of acquired epilepsy, but treatment for preventing the
development of post-stroke epilepsy is still unavailable. Since stroke results in neuronal …

Alpha-asarone, a major active component isolated from Acorus gramineus, can affect brain
functions and behaviors by multiple mechanisms. However, the effect of alpha-asarone on …

Microglial phagocytosis benefits neurological recovery after stroke. Large-conductance
Ca2+-activated K+ currents are expressed in activated microglia, and BK channel knockout …

Blood-brain barrier (BBB) disruption underlies the vasogenic edema and neuronal cell
death induced by acute ischemic stroke. Reducing this disruption has therapeutic potential …

Cyclin B2 (CCNB2) belongs to type B cell cycle family protein, which is located on
chromosome 15q22, and it binds to cyclin-dependent kinases (CDKs) to regulate their …

Ischemic damage in brain tissue triggers a cascade of molecular and structural plastic
changes, thus influencing a wide range of cell-to-cell interactions. Understanding and …