Synaptic abnormalities are a cardinal feature of Alzheimer's disease (AD) that are known to
arise as the disease progresses. A growing body of evidence suggests that pathological …

Neurotrophins, such as brain-derived neurotrophic factor (BDNF), are essential for neuronal
survival and growth. The signaling cascades initiated by BDNF and its receptor are the key …

It is well known that brain-derived neurotrophic factor, BDNF, has an important role in a
variety of neuronal aspects, such as differentiation, maturation, and synaptic function in the …

Aging is a normal physiological process accompanied by cognitive decline. This aging
process has been the primary risk factor for development of aging-related diseases such as …

Neurotrophic factors comprise essential secreted proteins that have several functions in
neural and non-neural tissues, mediating the development, survival and maintenance of …

Alzheimer's disease (AD) is the most common type of dementia and a neurodegenerative
disorder characterized by memory deficits especially forgetting recent information, recall …

This review is focused on several psychiatric disorders in which cognitive impairment is a
major component of the disease, influencing life quality. There are plenty of data proving that …

Brain-Derived Neurotrophic Factor (BDNF) is a dominant neurotrophic factor in the brain
which plays a crucial role in differentiation, regeneration and plasticity mechanisms. Binding …

Neuronal cell injury, as a consequence of acute or chronic neurological trauma, is a
significant cause of mortality around the world. On a molecular level, the condition is …

Studies suggest that dysfunction of brain-derived neurotrophic factor (BDNF) is a possible
contributor to the pathology and symptoms of Alzheimer's disease (AD). Several studies …