Non‐T2 asthma is traditionally defined as asthma without features of T2 asthma. The
definition is arbitrary and is generally based on the presence of neutrophils in sputum, or the …

The term “eosinophilic” asthma (EA) generally refers to the clinical inflammatory phenotype
of asthma wherein a significant number of sputum, airway, and/or blood eosinophils are …

Although asthma is very common, affecting 5–10% of the population, the diagnosis of
asthma in adults remains a challenge in the real world, which results in both over-and under …

Eosinophilic inflammation is a feature of allergic asthma. Despite mounting evidence
showing that chromatin filaments released from neutrophils mediate various diseases, the …

Inflammation, structural, and functional abnormalities within the airways are key features of
asthma. Although these processes are well documented, their expression varies across the …

Rationale: Analysis of exhaled breath for asthma phenotyping using endogenously
generated volatile organic compounds (VOCs) offers the possibility of noninvasive diagnosis …

Among patients with asthma, heterogeneity exists regarding the pattern of airway
inflammation and response to treatment, prompting the necessity of recognizing specific …

The heterogeneity of asthma makes it challenging to unravel the pathophysiologic
mechanisms of the disease. Despite the wealth of research identifying diverse phenotypes …

Background The clinical context for using blood eosinophil (EOS) counts as treatment–
response biomarkers in asthma and COPD requires better understanding of EOS …

Asthma is classically described as having either a type 2 (T2) eosinophilic phenotype or a
non-T2 neutrophilic phenotype. T2 asthma usually responds to classical bronchodilation …