Neglected tropical diseases (NTDs) as termed by WHO include twenty different infectious
diseases that are caused by bacteria, viruses, and parasites. Among these NTDs, Chagas …

Leishmaniasis is a parasitic disease that presents four main clinical syndromes: cutaneous
leishmaniasis (CL), mucocutaneous leishmaniasis (MCL), visceral leishmaniasis/kala azar …

A catalytic regime for the direct phosphatation of simple, non‐polarized alkenes has been
devised that is based on using ordinary, non‐activated phosphoric acid diesters as the …

Miltefosine (MF), an alkylphospholipid originally developed for breast cancer treatment, is a
highly active drug for the treatment against leishmaniasis, a neglected tropical disease …

Although miltefosine and paromomycin were registered as clinical agents against visceral
leishmaniasis in the last decade, the antileishmanial drug arsenal still requires …

Miltefosine presents antineoplastic activity but high hemolytic potential. Its use in cancer has
been limited to treating cutaneous metastasis of breast cancer. To decrease hemolytic …

Scedosporium and Lomentospora species are filamentous fungi responsible for a wide
range of infections in humans and are frequently associated with cystic fibrosis and …

Objectives The aim of this study was to evaluate miltefosine and four synthetic compounds
(TCAN26, TC19, TC106 and TC117) for their in vitro inhibitory activity against Candida …

A series of 16 simple long-chain alkyltriazoles and two novel alkylphosphocholine
derivatives containing an azide moiety were evaluated in vitro for their leishmanicidal activity …

In the present study, glycyrrhizic acid (GA) the main component of Glycyrrhiza glabra was
evaluated for its efficacy as antileishmanial agent and its mode of action explored. GA …