[HTML][HTML] The evolving landscape of sex-based differences in lung cancer: a distinct disease in women

M Ragavan, MI Patel - European Respiratory Review, 2022 - Eur Respiratory Soc
In stark contrast to a few decades ago when lung cancer was predominantly a disease of
men who smoke, incidence rates of lung cancer in women are now comparable to or higher …

[HTML][HTML] Gender-specific aspects of epidemiology, molecular genetics and outcome: lung cancer

N Mederos, A Friedlaender, S Peters, A Addeo - ESMO open, 2020 - Elsevier
Lung cancer remains the leading cause of cancer-related deaths worldwide in women and
men. In incidence, lung cancer ranks second, surpassed by breast cancer in women and …

Carboplatin and pemetrexed with or without pembrolizumab for advanced, non-squamous non-small-cell lung cancer: a randomised, phase 2 cohort of the open-label …

CJ Langer, SM Gadgeel, H Borghaei… - The lancet …, 2016 - thelancet.com
Background Limited evidence exists to show that adding a third agent to platinum-doublet
chemotherapy improves efficacy in the first-line advanced non-small-cell lung cancer …

Sex differences in efficacy and toxicity of systemic treatments: an undervalued issue in the era of precision oncology.

BC Özdemir, C Csajka, GP Dotto… - Journal of clinical …, 2018 - europepmc.org
Sex Differences in Efficacy and Toxicity of Systemic Treatments: An Undervalued Issue in the
Era of Precision Oncology. - Abstract - Europe PMC Sign in | Create an account https://orcid.org …

First-line erlotinib in patients with advanced non-small-cell lung cancer unsuitable for chemotherapy (TOPICAL): a double-blind, placebo-controlled, phase 3 trial

SM Lee, I Khan, S Upadhyay, C Lewanski… - The lancet …, 2012 - thelancet.com
Background Many patients with advanced non-small-cell lung cancer (NSCLC) receive only
active supportive care because of poor performance status or presence of several …

[HTML][HTML] Evaluating prognostic factors for sex differences in lung cancer survival: findings from a large Australian cohort

XQ Yu, ML Yap, ES Cheng, PJ Ngo… - Journal of Thoracic …, 2022 - Elsevier
Introduction Women tend to survive a lung cancer diagnosis longer than men; however
potential drivers of this sex-related disparity remain largely elusive. We quantified factors …

Genetic and modifiable risk factors contributing to cisplatin-induced toxicities

MR Trendowski, O El Charif, PC Dinh Jr, LB Travis… - Clinical Cancer …, 2019 - AACR
Effective administration of traditional cytotoxic chemotherapy is often limited by off-target
toxicities. This clinical dilemma is epitomized by cisplatin, a platinating agent, which has …

Lung cancer in women: a modern epidemic

CR MacRosty, MP Rivera - Clinics in chest medicine, 2020 - chestmed.theclinics.com
Lung cancer remains a significant health problem worldwide for both men and women and
is the leading cause of cancer death in many countries. Age-adjusted lung cancer incidence …

Abnormal expression of the pre-mRNA splicing regulators SRSF1, SRSF2, SRPK1 and SRPK2 in non small cell lung carcinoma

S Gout, E Brambilla, A Boudria, R Drissi, S Lantuejoul… - 2012 - journals.plos.org
Splicing abnormalities frequently occur in cancer. A key role as splice site choice regulator is
played by the members of the SR (Ser/Arg-rich) family of proteins. We recently demonstrated …

Sex differences in the efficacy of immune checkpoint inhibitors in neoadjuvant therapy of non-small cell lung cancer: a meta-analysis

G Suay, JC Garcia-Cañaveras, F Aparisi, A Lahoz… - Cancers, 2023 - mdpi.com
Simple Summary Immune checkpoint inhibitors (ICIs) have transformed the treatment
paradigm for metastatic non-small cell lung cancer (NSCLC) patients (IB-IIIA) with no …