MicroRNA regulation of RNA virus replication and pathogenesis

DW Trobaugh, WB Klimstra - Trends in molecular medicine, 2017 - cell.com
microRNAs (miRNAs) are non-coding RNAs that regulate many processes within a cell by
manipulating protein levels through direct binding to mRNA and influencing translation …

Stress proteins: the biological functions in virus infection, present and challenges for target-based antiviral drug development

Q Wan, D Song, H Li, M He - Signal transduction and targeted therapy, 2020 - nature.com
Stress proteins (SPs) including heat-shock proteins (HSPs), RNA chaperones, and ER
associated stress proteins are molecular chaperones essential for cellular homeostasis. The …

On the importance of host microRNAs during viral infection

E Girardi, P López, S Pfeffer - Frontiers in genetics, 2018 - frontiersin.org
Every living organism has to constantly face threats from the environment and deal with a
large number of pathogens against which it has to defend itself to survive. Among those …

The clinical application of microRNAs in infectious disease

RE Drury, D O'Connor, AJ Pollard - Frontiers in immunology, 2017 - frontiersin.org
MicroRNAs (miRNAs) are short single-stranded non-coding RNA sequences that
posttranscriptionally regulate up to 60% of protein encoding genes. Evidence is emerging …

Broad-spectrum inhibition of respiratory virus infection by microRNA mimics targeting p38 MAPK signaling

JL McCaskill, S Ressel, A Alber, J Redford… - … Therapy-Nucleic Acids, 2017 - cell.com
The majority of antiviral therapeutics target conserved viral proteins, however, this approach
confers selective pressure on the virus and increases the probability of antiviral drug …

MicroRNA-focused CRISPR-Cas9 library screen reveals fitness-associated miRNAs

JS Kurata, RJ Lin - Rna, 2018 - rnajournal.cshlp.org
MicroRNAs (miRNAs) are post-transcriptional gene regulators that play important roles in
the control of cell fitness, differentiation, and development. The CRISPR-Cas9 gene-editing …

Anti-NMDA receptor encephalitis and vaccination

H Wang - International journal of molecular sciences, 2017 - mdpi.com
Anti-N-methyl-d-aspartate (Anti-NMDA) receptor encephalitis is an acute autoimmune
neurological disorder. The cause of this disease is often unknown, and previous studies …

Persistent enterovirus infection: little deletions, long infections

NM Chapman - Vaccines, 2022 - mdpi.com
Enteroviruses have now been shown to persist in cell cultures and in vivo by a novel
mechanism involving the deletion of varying amounts of the 5′ terminal genomic region …

The potential therapeutic effect of RNA interference and natural products on COVID-19: a review of the coronaviruses infection

MR Kalhori, F Saadatpour, E Arefian… - Frontiers in …, 2021 - frontiersin.org
The SARS-CoV-2 virus was reported for the first time in Wuhan, Hubei Province, China, and
causes respiratory infection. This pandemic pneumonia killed about 1,437,835 people out of …

Anti-NMDA receptor encephalitis, vaccination and virus

H Wang - Current Pharmaceutical Design, 2019 - ingentaconnect.com
Anti-N-methyl-d-aspartate (Anti-NMDA) receptor encephalitis is an acute autoimmune
disorder. The symptoms range from psychiatric symptoms, movement disorders, cognitive …