Simple Summary Tau is an important protein for maintaining the shape and normal function
of nerve cells. There are many diseases that are identified by changes in this protein, yet …

Attenuating acetylcholinesterase and insulin/insulin-like growth factor-1 signaling in the
hippocampus is associated with Alzheimer's disease (AD) development. Fucoidan and …

Natural aging encompasses physiological and psychological changes that impact overall
health and quality of life. Mitigating these effects requires physical and mental exercise …

Arginases are often overexpressed in human diseases, and they are an important target for
developing anti-aging and antineoplastic drugs. Arginase type 1 (ARG1) is a cytosolic …

Laminaria digitata, a brown seaweed with prebiotic properties, can potentially enhance the
resilience of weaned piglets to nutritional distress. However, their cell wall polysaccharides …

A long-term intake of a high-fat and high-fructose diet (HFFD), even a high-fat, high-fructose
but low-protein diet (HFFD+ LP), could cause obesity associated with cognitive impairments …

Background: Disturbed metabolism has been proposed as being involved in the
pathogenesis of Alzheimer's disease (AD), and more evidence from human AD brains is …

Human tauopathies are characterized by intracellular aggregation of hyperphosphorylated
tau protein in neurons. Tau is involved in many cellular functions through its association with …

Despite our best efforts to discover new antimicrobials, bacteria have evolved mechanisms
to become resistant. Resistance to antimicrobials can be attributed to innate, inducible, and …