Environmental epigenetics describes how environmental factors affect cellular epigenetics
and, hence, human health. Epigenetic marks alter the spatial conformation of chromatin to …

Abstract The Endocrine Society's first Scientific Statement in 2009 provided a wake-up call to
the scientific community about how environmental endocrine-disrupting chemicals (EDCs) …

How obesity and elevated androgen levels in women with polycystic ovary syndrome
(PCOS) affect their offspring is unclear. In a Swedish nationwide register-based cohort and a …

Extensive experimental animal studies and epidemiological observations have shown that
environmental influences during early development affect the risk of later pathophysiological …

INTRODUCTION Despite the father transmitting half of the heritable information to the
embryo, the focus of preconception health has been the mother. Paternal effects have been …

Environmental compounds are known to promote epigenetic transgenerational inheritance
of adult onset disease in subsequent generations (F1–F3) following ancestral exposure …

The evidence in support of the developmental origins of the health and disease paradigm is
sufficiently robust and repeatable across species, including humans, to suggest a need for …

BACKGROUND A defining feature of sexual reproduction is the transmission of genomic
information from both parents to the offspring. There is now compelling evidence that the …

Endocrine disrupting chemicals (EDCs), including the mass-produced component of
plastics, bisphenol A (BPA) are widely prevalent in aquatic and terrestrial habitats. Many …

Environmental factors during fetal development can induce a permanent epigenetic change
in the germ line (sperm) that then transmits epigenetic transgenerational inheritance of adult …