Tight junctions (TJs) are intercellular junctions critical for building the epithelial barrier and
maintaining epithelial polarity. The claudin family of membrane proteins play central roles in …

The ability of epithelial cells to organize through cell–cell adhesion into a functioning
epithelium serves the purpose of a tight epithelial protective barrier. Contacts between …

The intestinal epithelium forms a highly dynamic and selective barrier that controls
absorption of fluid and solutes while restricting pathogen access to underlying tissues …

Claudins are tight junction membrane proteins that are expressed in epithelia and
endothelia and form paracellular barriers and pores that determine tight junction …

The tight junction creates an intercellular barrier limiting paracellular movement of solutes
and material across epithelia. Currently many proteins have been identified as components …

Claudins are tetraspan transmembrane proteins of tight junctions. They determine the
barrier properties of this type of cell–cell contact existing between the plasma membranes of …

Cell–cell apical junctions of epithelia consist of multiprotein complexes that organize as
belts regulating cell–cell adhesion, permeability, and mechanical tension: the tight junction …

The morphological feature of tight junctions (TJs) fits well with their functions. The core of TJs
is a fibril-like proteinaceous structure within the lipid bilayer, the so-called TJ strands. TJ …

Mammals have an astonishing ability to sense and discriminate sounds of different
frequencies and intensities. Fundamental for this process are mechanosensory hair cells in …

Tricellular tight junctions (tTJs) seal the extracellular space at tricellular contacts (TCs),
where the corners of three epithelial cells meet. To date, the transmembrane proteins …