Validated pretreatment prediction models for response to neoadjuvant therapy in patients with rectal cancer: a systematic review and critical appraisal
MD Tanaka, BM Geubels, BA Grotenhuis… - Cancers, 2023 - mdpi.com
Simple Summary Organ preservation strategies can be offered to patients with rectal cancer
that show a strong response to preoperative treatment in order to avoid major surgery …
that show a strong response to preoperative treatment in order to avoid major surgery …
Identifying plasma metabolic characteristics of major depressive disorder, bipolar disorder, and schizophrenia in adolescents
B Yin, Y Cai, T Teng, X Wang, X Liu, X Li… - Translational …, 2024 - nature.com
Major depressive disorder (MDD), bipolar disorder (BD), and schizophrenia (SCZ) are
classified as major mental disorders and together account for the second-highest global …
classified as major mental disorders and together account for the second-highest global …
High-Throughput Metabolic Pattern Screening Strategy for Early Colorectal and Gastric Cancers Based on Covalent Organic Frameworks-Assisted Laser Desorption …
C Yang, H Yu, W Li, H Lin, H Wu, C Deng - Analytical Chemistry, 2024 - ACS Publications
Precise early diagnosis and staging are conducive to improving the prognosis of colorectal
cancer (CRC) and gastric cancer (GC) patients. However, due to intrusive inspections and …
cancer (CRC) and gastric cancer (GC) patients. However, due to intrusive inspections and …
Metabolic features of adolescent major depressive disorder: A comparative study between treatment-resistant depression and first-episode drug-naive depression
X Gan, X Li, Y Cai, B Yin, Q Pan, T Teng, Y He… - …, 2024 - Elsevier
Major depressive disorder (MDD) is a psychiatric illness that can jeopardize the normal
growth and development of adolescents. Approximately 40% of adolescent patients with …
growth and development of adolescents. Approximately 40% of adolescent patients with …
Image-based consensus molecular subtyping in rectal cancer biopsies and response to neoadjuvant chemoradiotherapy
The development of deep learning (DL) models to predict the consensus molecular
subtypes (CMS) from histopathology images (imCMS) is a promising and cost-effective …
subtypes (CMS) from histopathology images (imCMS) is a promising and cost-effective …
Ginsenoside Rh4 alleviates gastrointestinal mucositis and enhances chemotherapy efficacy through modulating gut microbiota
X Bai, J Deng, Z Duan, R Fu, C Zhu, D Fan - Phytomedicine, 2024 - Elsevier
Background Gastrointestinal mucositis stands as one of the most severe side effects of
irinotecan (CPT-11). however, only palliative treatment is available at present. Therefore …
irinotecan (CPT-11). however, only palliative treatment is available at present. Therefore …
LC–MS metabolomics analysis of serum metabolites during neoadjuvant chemoradiotherapy in locally advanced rectal cancer
Q Peng, L Jiang, Y Shen, Y Xu, X Shen, L Zou… - Clinical and …, 2024 - Springer
Background This study aimed to investigate the serum metabolite profiles during
neoadjuvant chemoradiotherapy (NCRT) in locally advanced rectal cancer (LARC) using …
neoadjuvant chemoradiotherapy (NCRT) in locally advanced rectal cancer (LARC) using …
Multiomic traits reveal critical irinotecan-related regulators in colorectal cancer, and irinotecan promotes ferroptosis in colorectal cancer by regulating FSTL3
C Huang, B Tang, H Lan, J Chen, H Shen, J Jiang… - 2023 - researchsquare.com
Background: Irinotecan is a widely used chemotherapy drug in colorectal cancer (CRC). The
evolution and prognosis of CRC involve complex mechanisms and depend on the drug …
evolution and prognosis of CRC involve complex mechanisms and depend on the drug …
Multi-dataset study on neoadjuvant treatment-related prognostic model and molecular network mechanism of locally advanced rectal cancer
W Su, Y Wu, C Xing - 2024 - researchsquare.com
Results A total of 633 differentially expressed genes associated with nCRT were identified,
comprising 238 up-regulated and 395 down-regulated genes. These genes are …
comprising 238 up-regulated and 395 down-regulated genes. These genes are …