Dysregulation of adult hippocampal neuroplasticity in major depression: pathogenesis and therapeutic implications

AN Tartt, MB Mariani, R Hen, JJ Mann… - Molecular psychiatry, 2022 - nature.com
Major depressive disorder (MDD) was previously hypothesized to be a disease of
monoamine deficiency in which low levels of monoamines in the synaptic cleft were …

Adult hippocampal neurogenesis and cognitive flexibility—linking memory and mood

C Anacker, R Hen - Nature Reviews Neuroscience, 2017 - nature.com
Adult hippocampal neurogenesis has been implicated in cognitive processes, such as
pattern separation, and in the behavioural effects of stress and antidepressants. Young adult …

Dietary (poly) phenolics in human health: structures, bioavailability, and evidence of protective effects against chronic diseases

D Del Rio, A Rodriguez-Mateos… - Antioxidants & redox …, 2013 - liebertpub.com
Human intervention trials have provided evidence for protective effects of various (poly)
phenol-rich foods against chronic disease, including cardiovascular disease …

Regulation and function of adult neurogenesis: from genes to cognition

JB Aimone, Y Li, SW Lee… - Physiological …, 2014 - journals.physiology.org
Adult neurogenesis in the hippocampus is a notable process due not only to its uniqueness
and potential impact on cognition but also to its localized vertical integration of different …

Adult neurogenesis contributes to hippocampal plasticity

T Toda, FH Gage - Cell and tissue research, 2018 - Springer
Adult hippocampal neurogenesis is the process by which new functional neurons are added
to the adult dentate gyrus of the hippocampus. Animal studies have shown that the degree of …

Adult neurogenesis in the mammalian dentate gyrus

LC Abbott, F Nigussie - Anatomia, histologia, embryologia, 2020 - Wiley Online Library
Earlier observations in neuroscience suggested that no new neurons form in the mature
central nervous system. Evidence now indicates that new neurons do form in the adult …

New neurons and new memories: how does adult hippocampal neurogenesis affect learning and memory?

W Deng, JB Aimone, FH Gage - Nature reviews neuroscience, 2010 - nature.com
The integration of adult-born neurons into the circuitry of the adult hippocampus suggests an
important role for adult hippocampal neurogenesis in learning and memory, but its specific …

Adult neurogenesis, glia, and the extracellular matrix

EC Cope, E Gould - Cell Stem Cell, 2019 - cell.com
In the adult mammalian hippocampus, new neurons arise from stem and progenitor cell
division, in a process known as adult neurogenesis. Adult-generated neurons are sensitive …

The glial nature of embryonic and adult neural stem cells

A Kriegstein, A Alvarez-Buylla - Annual review of neuroscience, 2009 - annualreviews.org
Glial cells were long considered end products of neural differentiation, specialized
supportive cells with an origin very different from that of neurons. New studies have shown …

Neural mechanisms of stress resilience and vulnerability

TB Franklin, BJ Saab, IM Mansuy - Neuron, 2012 - cell.com
Exposure to stressful events can be differently perceived by individuals and can have
persistent sequelae depending on the level of stress resilience or vulnerability of each …