Understanding the genetic basis of variation in meiotic recombination: past, present, and future

SE Johnston - Molecular Biology and Evolution, 2024 - academic.oup.com
Meiotic recombination is a fundamental feature of sexually reproducing species. It is often
required for proper chromosome segregation and plays important role in adaptation and the …

Codon usage and codon pair patterns in non-grass monocot genomes

P Mazumdar, RY Binti Othman, K Mebus… - Annals of …, 2017 - academic.oup.com
Abstract Background and Aims Studies on codon usage in monocots have focused on
grasses, and observed patterns of this taxon were generalized to all monocot species. Here …

Long runs of homozygosity are enriched for deleterious variation

ZA Szpiech, J Xu, TJ Pemberton, W Peng… - The American Journal of …, 2013 - cell.com
Exome sequencing offers the potential to study the population-genomic variables that
underlie patterns of deleterious variation. Runs of homozygosity (ROH) are long stretches of …

Codon usage bias in animals: disentangling the effects of natural selection, effective population size, and GC-biased gene conversion

N Galtier, C Roux, M Rousselle… - Molecular biology …, 2018 - academic.oup.com
Selection on codon usage bias is well documented in a number of microorganisms. Whether
codon usage is also generally shaped by natural selection in large organisms, despite their …

GC-content evolution in bacterial genomes: the biased gene conversion hypothesis expands

F Lassalle, S Périan, T Bataillon, X Nesme… - PLoS …, 2015 - journals.plos.org
The characterization of functional elements in genomes relies on the identification of the
footprints of natural selection. In this quest, taking into account neutral evolutionary …

Less is more in mammalian phylogenomics: AT-rich genes minimize tree conflicts and unravel the root of placental mammals

J Romiguier, V Ranwez, F Delsuc… - Molecular biology …, 2013 - academic.oup.com
Despite the rapid increase of size in phylogenomic data sets, a number of important nodes
on animal phylogeny are still unresolved. Among these, the rooting of the placental mammal …

Quantification of GC-biased gene conversion in the human genome

S Glémin, PF Arndt, PW Messer, D Petrov… - Genome …, 2015 - genome.cshlp.org
Much evidence indicates that GC-biased gene conversion (gBGC) has a major impact on
the evolution of mammalian genomes. However, a detailed quantification of the process is …

Extreme Recombination Frequencies Shape Genome Variation and Evolution in the Honeybee, Apis mellifera

A Wallberg, S Glémin, MT Webster - PLoS Genetics, 2015 - journals.plos.org
Meiotic recombination is a fundamental cellular process, with important consequences for
evolution and genome integrity. However, we know little about how recombination rates vary …

Phylogenomics controlling for base compositional bias reveals a single origin of eusociality in corbiculate bees

J Romiguier, SA Cameron, SH Woodard… - Molecular biology …, 2016 - academic.oup.com
As increasingly large molecular data sets are collected for phylogenomics, the conflicting
phylogenetic signal among gene trees poses challenges to resolve some difficult nodes of …

Direct and indirect consequences of meiotic recombination: implications for genome evolution

MT Webster, LD Hurst - Trends in genetics, 2012 - cell.com
There is considerable variation within eukaryotic genomes in the local rate of crossing over.
Why is this and what effect does it have on genome evolution? On the genome scale, it is …