Tactile sensory information from facial whiskers provides nocturnal tunnel-dwelling rodents,
including mice and rats, with important spatial and textural information about their immediate …

Phosphoinositides (PIs) make up only a small fraction of cellular phospholipids, yet they
control almost all aspects of a cell's life and death. These lipids gained tremendous research …

The tactile somatosensory pathway from whisker to cortex in rodents provides a well-defined
system for exploring the link between molecular mechanisms, synaptic circuits, and …

In primary sensory neocortical areas of mammals, the distribution of sensory receptors is
mapped with topographic precision and amplification in proportion to the peripheral receptor …

Metabotropic glutamate receptors (mGlus) are a family of G-protein-coupled receptors
activated by the neurotransmitter glutamate. Molecular cloning has revealed eight different …

The arealization of the mammalian cortex is believed to be controlled by a combination of
intrinsic factors that are expressed in the cortex, and external signals, some of which are …

Environmental stimulation throughout development adjusts the neurobehavioral systems
involved in learning, memory and defensive responses. Environment-mediated phenotypic …

Alterations in sensory processing constitute prominent symptoms of fragile X syndrome;
however, little is known about how disrupted synaptic and circuit development in sensory …

Huntington's disease is a genetic disorder that causes motor dysfunction, personality
changes, dementia, and premature death. There is currently no effective therapy. Several …

The CCCTC-binding factor (CTCF) is a key molecule for chromatin conformational changes
that promote cellular diversity, but nothing is known about its role in neurons. Here, we …