Phenotypic Screening in C. elegans as a Tool for the Discovery of New Geroprotective Drugs

S Bulterijs, BP Braeckman - Pharmaceuticals, 2020 - mdpi.com
Population aging is one of the largest challenges of the 21st century. As more people live to
advanced ages, the prevalence of age-related diseases and disabilities will increase …

Using a Caenorhabditis elegans Parkinson's Disease Model to Assess Disease Progression and Therapy Efficiency

S Hughes, M van Dop, N Kolsters, D van de Klashorst… - Pharmaceuticals, 2022 - mdpi.com
Despite Parkinson's Disease (PD) being the second most common neurodegenerative
disease, treatment options are limited. Consequently, there is an urgent need to identify and …

Prediction of biological age by morphological staging of sarcopenia in Caenorhabditis elegans

I Dhondt, C Verschuuren, A Zečić… - Disease models & …, 2021 - journals.biologists.com
Sarcopenia encompasses a progressive decline in muscle quantity and quality. Given its
close association with ageing, it may represent a valuable healthspan marker. The …

Caenorhabditis elegans Multi-Tracker Based on a Modified Skeleton Algorithm

PE Layana Castro, JC Puchalt, A García Garví… - Sensors, 2021 - mdpi.com
Automatic tracking of Caenorhabditis elegans (C. egans) in standard Petri dishes is
challenging due to high-resolution image requirements when fully monitoring a Petri dish …

[HTML][HTML] A high-throughput microplate toxicity screening platform based on Caenorhabditis elegans

J Wu, Y Gao, J Xi, X You, X Zhang, X Zhang… - Ecotoxicology and …, 2022 - Elsevier
Abstract Caenorhabditis elegans (C. elegans), an established model organism, has been
widely used in environmental toxicology research. However, most of the current toxicity …

Improving skeleton algorithm for helping Caenorhabditis elegans trackers

PE Layana Castro, JC Puchalt… - Scientific Reports, 2020 - nature.com
One of the main problems when monitoring Caenorhabditis elegans nematodes (C.
elegans) is tracking their poses by automatic computer vision systems. This is a challenge …

Desarrollo de técnicas avanzadas de seguimiento de posturas para reconocimiento de comportamientos de C. elegans

PE Layana Castro - 2023 - riunet.upv.es
[ES] El objetivo principal de esta tesis es el desarrollo de técnicas avanzadas de
seguimiento de posturas para reconocimiento de comportamientos del Caenorhabditis …

Regulation of Stress-Induced Longevity

H Miller - 2021 - deepblue.lib.umich.edu
Rapid advances in aging research have identified several stressful stimuli (eg food/oxygen
availability, temperature) that can enhance health and longevity across taxa. Many of these …