Activity-dependent spinal cord neuromodulation rapidly restores trunk and leg motor functions after complete paralysis

A Rowald, S Komi, R Demesmaeker, E Baaklini… - Nature medicine, 2022 - nature.com
Epidural electrical stimulation (EES) targeting the dorsal roots of lumbosacral segments
restores walking in people with spinal cord injury (SCI). However, EES is delivered with …

[HTML][HTML] The 2023 yearbook of Neurorestoratology

H Huang, JR Bach, HS Sharma, L Chen, P Wu… - Journal of …, 2024 - Elsevier
Remarkable advancements have been made in understanding the pathogenesis of
Alzheimer's disease, Parkinson's disease, and other neurological disease; in our depth of …

[HTML][HTML] Restoring sensorimotor function through neuromodulation after spinal cord injury: progress and remaining challenges

H Zhang, Y Liu, K Zhou, W Wei, Y Liu - Frontiers in Neuroscience, 2021 - frontiersin.org
Spinal cord injury (SCI) is a major disability that results in motor and sensory impairment and
extensive complications for the affected individuals which not only affect the quality of life of …

[HTML][HTML] Combined transcutaneous electrical spinal cord stimulation and task-specific rehabilitation improves trunk and sitting functions in people with chronic …

NS Tharu, M Alam, YT Ling, AYL Wong, YP Zheng - Biomedicines, 2022 - mdpi.com
The aim of this study was to examine the effects of transcutaneous electrical spinal cord
stimulation (TSCS) and conventional task-specific rehabilitation (TSR) on trunk control and …

[HTML][HTML] Clinical guidelines for neurorestorative therapies in spinal cord injury (2021 China version)

X Guo, Y Feng, T Sun, S Feng, J Tang, L Chen… - Journal of …, 2021 - Elsevier
Treatment of spinal cord injury (SCI) remains challenging. Considering the rapid
developments in neurorestorative therapies for SCI, we have revised and updated the …

[HTML][HTML] Multi-site spinal cord transcutaneous stimulation facilitates upper limb sensory and motor recovery in severe cervical spinal cord injury: a case study

P Sharma, T Panta, B Ugiliweneza, RJ Bert… - Journal of Clinical …, 2023 - mdpi.com
Individuals with cervical spinal cord injury (SCI) rank regaining arm and hand function as
their top rehabilitation priority post-injury. Cervical spinal cord transcutaneous stimulation …

Axon regeneration: a subcellular extension in multiple dimensions

CC Winter, Z He, A Jacobi - Cold Spring Harbor …, 2022 - cshperspectives.cshlp.org
Axons are a unique cellular structure that allows for the communication between neurons.
Axon damage compromises neuronal communications and often leads to functional deficits …

[HTML][HTML] Invasive and non-invasive approaches of electrical stimulation to improve physical functioning after spinal cord injury

DR Dolbow, AS Gorgey, TW Sutor… - Journal of Clinical …, 2021 - mdpi.com
This review of literature provides the latest evidence involving invasive and non-invasive
uses of electrical stimulation therapies that assist in restoring functional abilities and the …

Historical development and contemporary use of neuromodulation in human spinal cord injury

S Harkema, C Angeli… - Current Opinion in …, 2022 - journals.lww.com
The discovery that both motor and autonomic function recovers with lumbosacral spinal cord
placement of the electrode reveals exciting avenues for a synergistic overall improvement in …

[HTML][HTML] Voluntary modulation of evoked responses generated by epidural and transcutaneous spinal stimulation in humans with spinal cord injury

JS Calvert, ML Gill, MB Linde, DD Veith… - Journal of clinical …, 2021 - mdpi.com
Transcutaneous (TSS) and epidural spinal stimulation (ESS) are electrophysiological
techniques that have been used to investigate the interactions between exogenous …