Comprehensive meta-analysis, co-expression, and miRNA nested network analysis identifies gene candidates in citrus against Huanglongbing disease
Background Huanglongbing (HLB), the most devastating disease of citrus, is associated with
infection by Candidatus Liberibacter asiaticus (Ca Las) and is vectored by the Asian citrus …
infection by Candidatus Liberibacter asiaticus (Ca Las) and is vectored by the Asian citrus …
Integrative computational approach identifies drug targets in CD4+ T-cell-mediated immune disorders
CD4+ T cells provide adaptive immunity against pathogens and abnormal cells, and they
are also associated with various immune-related diseases. CD4+ T cells' metabolism is …
are also associated with various immune-related diseases. CD4+ T cells' metabolism is …
Identification of prognostic markers of high grade prostate cancer through an integrated bioinformatics approach
H Huang, Q Zhang, C Ye, JM Lv, X Liu, L Chen… - Journal of Cancer …, 2017 - Springer
Purpose Prostate cancer is one of the leading causes of cancer death for male. In the
present study, we applied an integrated bioinformatics approach to provide a novel …
present study, we applied an integrated bioinformatics approach to provide a novel …
Coexpression network analysis of human candida infection reveals key modules and hub genes responsible for host-pathogen interactions
S Naik, A Mohammed - Frontiers in Genetics, 2022 - frontiersin.org
Invasive fungal infections are a significant reason for morbidity and mortality among organ
transplant recipients. Therefore, it is critical to investigate the host and candida niches to …
transplant recipients. Therefore, it is critical to investigate the host and candida niches to …
Inhibition of Mycobacterium tuberculosis dihydrodipicolinate synthase by alpha-ketopimelic acid and its other structural analogues
The Mycobacterium tuberculosis dihydrodipicolinate synthase (Mtb-dapA) is an essential
gene. Mtb-DapA catalyzes the aldol condensation between pyruvate and L-aspartate-beta …
gene. Mtb-DapA catalyzes the aldol condensation between pyruvate and L-aspartate-beta …
Systems perturbation analysis of a large-scale signal transduction model reveals potentially influential candidates for cancer therapeutics
BL Puniya, L Allen, C Hochfelder… - … in Bioengineering and …, 2016 - frontiersin.org
Dysregulation in signal transduction pathways can lead to a variety of complex disorders,
including cancer. Computational approaches such as network analysis are important tools to …
including cancer. Computational approaches such as network analysis are important tools to …
Rat hepatocytes weighted gene co-expression network analysis identifies specific modules and hub genes related to liver regeneration after partial hepatectomy
Y Zhou, J Xu, Y Liu, J Li, C Chang, C Xu - PLoS One, 2014 - journals.plos.org
The recovery of liver mass is mainly mediated by proliferation of hepatocytes after 2/3 partial
hepatectomy (PH) in rats. Studying the gene expression profiles of hepatocytes after 2/3 PH …
hepatectomy (PH) in rats. Studying the gene expression profiles of hepatocytes after 2/3 PH …
Comparison of gene co-expression networks in Pseudomonas aeruginosa and Staphylococcus aureus reveals conservation in some aspects of virulence
Pseudomonas aeruginosa and Staphylococcus aureus are two evolutionary distant bacterial
species that are frequently isolated from persistent infections such as chronic infectious …
species that are frequently isolated from persistent infections such as chronic infectious …
Construction and verification of the transcriptional regulatory response network of Streptococcus mutansupon treatment with the biofilm inhibitor carolacton
Background Carolacton is a newly identified secondary metabolite causing altered cell
morphology and death of Streptococcus mutans biofilm cells. To unravel key regulators …
morphology and death of Streptococcus mutans biofilm cells. To unravel key regulators …
Integrative network analyses of transcriptomics data reveal potential drug targets for acute radiation syndrome
Recent political unrest has highlighted the importance of understanding the short-and long-
term effects of gamma-radiation exposure on human health and survivability. In this regard …
term effects of gamma-radiation exposure on human health and survivability. In this regard …