Droplet microfluidics for microbiology: techniques, applications and challenges

TS Kaminski, O Scheler, P Garstecki - Lab on a Chip, 2016 - pubs.rsc.org
Droplet microfluidics has rapidly emerged as one of the key technologies opening up new
experimental possibilities in microbiology. The ability to generate, manipulate and monitor …

Concentration gradient generation methods based on microfluidic systems

X Wang, Z Liu, Y Pang - RSC advances, 2017 - pubs.rsc.org
Various concentration gradient generation methods based on microfluidic systems are
summarized in this paper. The review covers typical structural characteristics, gradient …

Monitoring biomolecule concentrations in tissue using a wearable droplet microfluidic-based sensor

AM Nightingale, CL Leong, RA Burnish… - Nature …, 2019 - nature.com
Knowing how biomarker levels vary within biological fluids over time can produce valuable
insight into tissue physiology and pathology, and could inform personalised clinical …

Droplet-based microfluidics at the femtolitre scale

M Leman, F Abouakil, AD Griffiths, P Tabeling - Lab on a Chip, 2015 - pubs.rsc.org
We have built a toolbox of modules for droplet-based microfluidic operations on femtolitre
volume droplets. We have demonstrated monodisperse production, sorting, coalescence …

Droplet manipulations in two phase flow microfluidics

AM Pit, MHG Duits, F Mugele - Micromachines, 2015 - mdpi.com
Even though droplet microfluidics has been developed since the early 1980s, the number of
applications that have resulted in commercial products is still relatively small. This is partly …

A microfluidic chip integrated with droplet generation, pairing, trapping, merging, mixing and releasing

X Chen, CL Ren - RSC advances, 2017 - pubs.rsc.org
Developing a microfluidic chip with multiple functions is highly demanded for practical
applications, such as chemical analysis, diagnostics, particles synthesis and drug screening …

Microfluidic on-demand droplet generation, storage, retrieval, and merging for single-cell pairing

H Babahosseini, T Misteli, DL DeVoe - Lab on a Chip, 2019 - pubs.rsc.org
A multifunctional microfluidic platform combining on-demand aqueous-phase droplet
generation, multi-droplet storage, and controlled merging of droplets selected from a storage …

Droplet-interface-bilayer assays in microfluidic passive networks

B Schlicht, M Zagnoni - Scientific reports, 2015 - nature.com
Basic biophysical studies and pharmacological processes can be investigated by mimicking
the intracellular and extracellular environments across an artificial cell membrane construct …

A passive microfluidic system based on step emulsification allows the generation of libraries of nanoliter-sized droplets from microliter droplets of varying and known …

W Postek, TS Kaminski, P Garstecki - Lab on a Chip, 2017 - pubs.rsc.org
We present a novel geometry of microfluidic channels that allows us to passively generate
monodisperse emulsions of hundreds of droplets smaller than 1 nL from collections of larger …

From single-molecule detection to next-generation sequencing: microfluidic droplets for high-throughput nucleic acid analysis

Y Ding, J Choo, AJ DeMello - Microfluidics and nanofluidics, 2017 - Springer
Droplet-based microfluidic technologies have proved themselves to be of significant utility in
the performance of high-throughput chemical and biological experiments. By encapsulating …