Genetic factors are one of the basic determinants affecting ontogenesis in mammals.
Nevertheless, on the one hand, epigenetic factors have been found to exert the …

Although somatic cell nuclear transfer (SCNT) cloning is more efficient in cattle than in any
other species tested so far, there is a high rate of pregnancy failure that has been linked to …

In this study, we demonstrate the use of somatic cell nuclear transfer to produce the first
cloned camelid, a dromedary camel (Camelus dromedarius) belonging to the family …

Although cloning of mammals has been achieved successfully, the percentage of live
offspring is very low because of reduced fetal size and fewer implantation sites. Recent …

Ongoing detailed investigations into embryo–maternal communication before implantation
reveal that during early embryonic development a plethora of events are taking place …

Antibiotic selectable marker genes have been widely used to generate transgenic animals.
Once transgenic animals have been obtained, the selectable marker is no longer necessary …

We examined the effects of the source of recipient oocytes and timing of fusion and
activation on the development competence of bovine nuclear transferred (NT) embryos …

The period immediately after birth is a vital time for all newborn calves as the cardiovascular,
respiratory, and other organ systems adapt to life ex utero. Reported neonatal mortality rates …

Cloning by somatic cell nuclear transfer (SCNT) is characterized by low efficiency and the
occurrence of developmental abnormalities, which are rather poorly studied phenomena in …

Although a majority of clones are born normal and apparently healthy, mortality rates of
nearly 30% are described in many reports. Such losses are a major limitation of cloning …