The orisome: structure and function

AC Leonard, JE Grimwade - Frontiers in microbiology, 2015 - frontiersin.org
During the cell division cycle of all bacteria, DNA-protein complexes termed orisomes trigger
the onset of chromosome duplication. Orisome assembly is both staged and stringently …

Condensin-and replication-mediated bacterial chromosome folding and origin condensation revealed by Hi-C and super-resolution imaging

M Marbouty, A Le Gall, DI Cattoni, A Cournac, A Koh… - Molecular cell, 2015 - cell.com
Chromosomes of a broad range of species, from bacteria to mammals, are structured by
large topological domains whose precise functional roles and regulatory mechanisms …

Transcriptional activity of the bacterial replication initiator DnaA

IP Menikpurage, K Woo, PE Mera - Frontiers in microbiology, 2021 - frontiersin.org
In bacteria, DnaA is the most conserved DNA replication initiator protein. DnaA is a DNA
binding protein that is part of the AAA+ ATPase family. In addition to initiating chromosome …

Enhanced Recombinant Protein Productivity by Genome Reduction in Bacillus subtilis

T Morimoto, R Kadoya, K Endo, M Tohata… - DNA …, 2008 - academic.oup.com
The emerging field of synthetic genomics is expected to facilitate the generation of
microorganisms with the potential to achieve a sustainable society. One approach towards …

[HTML][HTML] Dynamic control of the DNA replication initiation protein DnaA by Soj/ParA

H Murray, J Errington - Cell, 2008 - cell.com
Regulation of DNA replication and segregation is essential for all cells. Orthologs of the
plasmid partitioning genes parA, parB, and parS are present in bacterial genomes …

The diversity and evolution of cell cycle regulation in alpha-proteobacteria: a comparative genomic analysis

M Brilli, M Fondi, R Fani, A Mengoni, L Ferri… - BMC systems …, 2010 - Springer
Abstract Background In the bacterium Caulobacter crescentus, CtrA coordinates DNA
replication, cell division, and polar morphogenesis and is considered the cell cycle master …

Cell size and the initiation of DNA replication in bacteria

NS Hill, R Kadoya, DK Chattoraj, PA Levin - PLoS genetics, 2012 - journals.plos.org
In eukaryotes, DNA replication is coupled to the cell cycle through the actions of cyclin-
dependent kinases and associated factors. In bacteria, the prevailing view, based primarily …

Genome-wide binding profiles of the Bacillus subtilis transition state regulator AbrB and its homolog Abh reveals their interactive role in transcriptional …

O Chumsakul, H Takahashi, T Oshima… - Nucleic acids …, 2011 - academic.oup.com
AbrB is a global transcriptional regulator of Bacillus subtilis that represses the expression of
many genes during exponential growth. Here, we demonstrate that AbrB and its homolog …

A mechanism for cell cycle regulation of sporulation initiation in Bacillus subtilis

JW Veening, H Murray, J Errington - Genes & development, 2009 - genesdev.cshlp.org
Coordination of DNA replication with cellular development is a crucial problem in most living
organisms. Bacillus subtilis cells switch from vegetative growth to sporulation when starved …

Noc protein binds to specific DNA sequences to coordinate cell division with chromosome segregation

LJ Wu, S Ishikawa, Y Kawai, T Oshima… - The EMBO …, 2009 - embopress.org
Coordination of chromosome segregation and cytokinesis is crucial for efficient cell
proliferation. In Bacillus subtilis, the nucleoid occlusion protein Noc protects the …