Chromosomes of a broad range of species, from bacteria to mammals, are structured by large topological domains whose precise functional roles and regulatory mechanisms …
IP Menikpurage, K Woo, PE Mera - Frontiers in microbiology, 2021 - frontiersin.org
In bacteria, DnaA is the most conserved DNA replication initiator protein. DnaA is a DNA binding protein that is part of the AAA+ ATPase family. In addition to initiating chromosome …
T Morimoto, R Kadoya, K Endo, M Tohata… - DNA …, 2008 - academic.oup.com
The emerging field of synthetic genomics is expected to facilitate the generation of microorganisms with the potential to achieve a sustainable society. One approach towards …
Regulation of DNA replication and segregation is essential for all cells. Orthologs of the plasmid partitioning genes parA, parB, and parS are present in bacterial genomes …
Abstract Background In the bacterium Caulobacter crescentus, CtrA coordinates DNA replication, cell division, and polar morphogenesis and is considered the cell cycle master …
In eukaryotes, DNA replication is coupled to the cell cycle through the actions of cyclin- dependent kinases and associated factors. In bacteria, the prevailing view, based primarily …
O Chumsakul, H Takahashi, T Oshima… - Nucleic acids …, 2011 - academic.oup.com
AbrB is a global transcriptional regulator of Bacillus subtilis that represses the expression of many genes during exponential growth. Here, we demonstrate that AbrB and its homolog …
Coordination of DNA replication with cellular development is a crucial problem in most living organisms. Bacillus subtilis cells switch from vegetative growth to sporulation when starved …
Coordination of chromosome segregation and cytokinesis is crucial for efficient cell proliferation. In Bacillus subtilis, the nucleoid occlusion protein Noc protects the …