Organ transplantation is undergoing profound changes. Contraindications for donation have
been revised in order to better meet the organ demand. The use of lower-quality organs and …

Lung transplantation is a life-saving treatment for patients with end stage lung disease. The
imbalance between lung graft supply and recipients has been a serious issue and barrier to …

Ex vivo lung perfusion (EVLP) is a data-intensive platform used for the assessment of
isolated lungs outside the body for transplantation; however, the integration of artificial …

Patients awaiting lung transplantation face high wait-list mortality, as injury precludes the
use of most donor lungs. Although ex vivo lung perfusion (EVLP) is able to recover marginal …

Ex vivo normothermic machine perfusion (NMP) of donor kidneys prior to transplantation
provides a platform for direct delivery of cellular therapeutics to optimize organ quality prior …

Background Ex vivo lung perfusion (EVLP) is an isolated organ assessment technique that
has revolutionized the field of lung transplantation and enabled a safe increase in the …

Disparities at the major histocompatibility complex (MHC) antigens and associated minor
antigens trigger harmful immune responses, leading to graft rejection after transplantation …

This article summarizes recent knowledge and clinical advances in machine perfusion (MP)
of thoracic organs. MP of thoracic organs has gained much attention during the last decade …

Despite the advancements in medical treatment, mechanical support, and stem cell therapy,
heart transplantation remains the most effective treatment for selected patients with …

Objectives Ex vivo lung perfusion provides an innovative method to assess and repair donor
lungs. The current Toronto ex vivo lung perfusion protocol can reliably and reproducibly …