Li–Fraumeni Syndrome: Mutation of TP53 Is a Biomarker of Hereditary Predisposition to Tumor: New Insights and Advances in the Treatment
Simple Summary Li–Fraumeni Syndrome (LFS) is a rare tumor predisposition syndrome in
which the tumor suppressor TP53 gene is mutated in the germ cell population. LFS patients …
which the tumor suppressor TP53 gene is mutated in the germ cell population. LFS patients …
[HTML][HTML] Genetic modifiers of p53: opportunities for breast cancer therapies
Each day our cells encounter a wide range of genomic damage and the p53 protein
arbitrates decisions of cell cycle arrest to allow repair of DNA or promote elimination of cells …
arbitrates decisions of cell cycle arrest to allow repair of DNA or promote elimination of cells …
Influence of genetic variations in miRNA and genes encoding proteins in the miRNA synthesis complex on toxicity of the treatment of pediatric B-Cell ALL in the …
E da Silva Menezes, FCA de Moraes… - International Journal of …, 2023 - mdpi.com
Acute lymphoblastic leukemia (ALL) is the most common childhood cancer in the world.
Single nucleotide variants (SNVs) in miRNA and genes encoding proteins of the miRNA …
Single nucleotide variants (SNVs) in miRNA and genes encoding proteins of the miRNA …
Functional pri-miR-34b/c rs4938723 and KRAS 3′ UTR rs61764370 SNPs: Novel phenotype modifiers in Li-Fraumeni Syndrome?
Abstract Purpose Li-Fraumeni Syndrome (LFS) is a rare cancer predisposing condition
caused by germline pathogenic TP53 variants, in which core tumors comprise sarcomas …
caused by germline pathogenic TP53 variants, in which core tumors comprise sarcomas …