A large body of evidence generated in the last two and a half years addresses the roles of T
cells in SARS-CoV-2 infection and following vaccination. Infection or vaccination induces …

SARS-CoV-2-specific T cell response has been proven essential for viral clearance, COVID-
19 outcome and long-term memory. Impaired early T cell-driven immunity leads to a severe …

The proliferation of single-cell multimodal sequencing technologies has enabled us to
understand cellular heterogeneity with multiple views, providing novel and actionable …

Key features of immune memory are greater and faster antigen-specific antibody responses
to repeat infection. In the setting of immune-evading viral evolution, it is important to …

ABSTRACT The coronavirus disease 2019 (COVID-19) has caused enormous health risks
and global economic disruption. This disease is caused by the severe acute respiratory …

The global rollout of COVID-19 vaccines has played a critical role in reducing pandemic
spread, disease severity, hospitalizations, and deaths. However, the first-generation …

Effective humoral immune responses require well-orchestrated B and T follicular helper (Tfh)
cell interactions. Whether these interactions are impaired and associated with COVID-19 …

Background The immune response to adenoviral COVID-19 vaccines is affected by the
interval between doses. The optimal interval is unknown. Aim We aim to explore in-silico the …

The rapid evolution of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)
has led to the emergence of new variants with different genetic profiles, with important …

Background & Aims Liver transplant recipients (LTRs) demonstrate a reduced response to
COVID-19 mRNA vaccination; however, a detailed understanding of the interplay between …