Bacteria in the genus Brucella are important human and veterinary pathogens. The abortion
and infertility they cause in food animals produce economic hardships in areas where the …

Brucella is an intracellular bacterium that causes abortion, reproduction failure in livestock
and leads to a debilitating flu-like illness with serious chronic complications if untreated in …

Brucella melitensis and Brucella ovis are the primary etiological agents of brucellosis in
small domestic ruminants. B. melitensis was first isolated in 1887 by David Bruce in Malta …

The facultative intracellular pathogen Brucella abortus interacts with several organelles of
the host cell to reach its replicative niche inside the endoplasmic reticulum. However, little is …

Brucellosis is a severe zoonotic infectious disease caused by the infection of the Brucella,
which is widespread and causes considerable economic losses in underdeveloped areas …

In response to danger signals, macrophages rapidly produce many inflammatory cytokines
that trigger the cascade release of inflammatory mediators, leading to tissue damage, which …

Invasive fungal infections pose a major threat to human health. Bacterial and protozoan
pathogens secrete protein effectors that overcome innate immune barriers to promote …

The unfolded protein response (UPR) is a homeostatic response to endoplasmic reticulum
(ER) stress within eukaryotic cells. The UPR initiates transcriptional and post-transcriptional …

Brucellosis is a serious zoonosis caused by Brucella spp. infection, which not only seriously
jeopardizes the health of humans and mammals, but also causes huge economic losses to …

Infection by Brucella species in pregnant animals and humans is associated with an
increased risk of abortion, preterm birth, and transmission of the infection to the offspring …