Nanofluidic structures have over the last two decades emerged as a powerful platform for
detailed analysis of DNA on the kilobase pair length scale. When DNA is confined to a …

The human genome contains multiple layers of information that extend beyond the genetic
sequence. In fact, identical genetics do not necessarily yield identical phenotypes as evident …

Owing to the technological advancements, including next generation sequencing, the
significance of deregulated epigenetic mechanisms in cancer initiation, progression and …

Nucleic acids are important biomarkers for disease detection, monitoring, and treatment.
Advances in technologies for nucleic acid analysis have enabled discovery and clinical …

DNA methylation, specifically, methylation of cytosine (C) nucleotides at the 5-carbon
position (5-mC), is the most studied and significant epigenetic modification. Here we …

This review (with 106 references) summarizes the latest progress in the synthesis, properties
and biomedical applications of gold nanotubes (AuNTs). Following an introduction into the …

Methylcytosine and 5‐hydroxymethylcytosine are epigenetic modifications involved in gene
regulation and cancer. We present a new, simple, and high‐throughput platform for multi …

Anorexia nervosa (AN) is a complex metabolic and psychological disorder that is influenced
by both heritable genetic components and environmental factors. Exposure to various …

Transcription factors (TFs) intricately navigate the vast genomic landscape to locate and
bind specific DNA sequences for the regulation of gene expression programs. These …

In this chapter, we have discussed the advancements in the conventional diagnoses and
their paradigm shift towards the affordable, sensitive, reliable, user-friendly, and deliverable …