Gene delivery by lipoplexes and polyplexes

CT de Ilarduya, Y Sun, N Düzgüneş - European journal of pharmaceutical …, 2010 - Elsevier
Gene therapy has emerged as a promising approach for the treatment or prevention of
acquired and genetic diseases. At the present time, major somatic gene transfer approaches …

Membrane electrostatics

G Cevc - Biochimica et Biophysica Acta (BBA)-Reviews on …, 1990 - Elsevier
Electrostatic phenomena play a crucial role in many biological processes. For membranes
they are signifi-

The complex nature of calcium cation interactions with phospholipid bilayers

A Melcrová, S Pokorna, S Pullanchery, M Kohagen… - Scientific reports, 2016 - nature.com
Understanding interactions of calcium with lipid membranes at the molecular level is of great
importance in light of their involvement in calcium signaling, association of proteins with …

KRas localizes to the plasma membrane by spatial cycles of solubilization, trapping and vesicular transport

M Schmick, N Vartak, B Papke, M Kovacevic… - Cell, 2014 - cell.com
KRas is a major proto-oncogene product whose signaling activity depends on its level of
enrichment on the plasma membrane (PM). This PM localization relies on posttranslational …

Current status of pH-sensitive liposomes in drug delivery

DC Drummond, M Zignani, JC Leroux - Progress in lipid research, 2000 - Elsevier
Liposomes are being increasingly utilized to deliver drugs, enzymes, antisense
oligonucleotides, and genes to various therapeutic targets. Liposome-mediated delivery of …

Fluorescence method for measuring the kinetics of fusion between biological membranes

D Hoekstra, T De Boer, K Klappe, J Wilschut - Biochemistry, 1984 - ACS Publications
Dick Hoekstra,* Tiny de Boer, Karin Klappe, and Jan Wilschut abstract: An assay is
presented that allows continuous and sensitive monitoring of membrane fusion in both …

Liposomes: preparation, characterization, and preservation

D Lichtenberg, Y Barenholz - Methods Biochem. Anal, 1988 - books.google.com
340 DOV LICHTENBERG AND YECHEZKEL BARENHOLZ edited by Gregoriadis (1984),
and most recently in a special issue of Chemistry and Physics of Lipids entitled …

Mechanisms and kinetics of liposome–cell interactions

N Düzgüneş, S Nir - Advanced drug delivery reviews, 1999 - Elsevier
Although the possibility of targeting drugs to specific tissues and cells, as well as facilitating
their uptake and cytoplasmic delivery has rendered liposomes a versatile drug carrier …

Biomembrane fusion: a new concept derived from model studies using two interacting planar lipid bilayers

LV Chernomordik, GB Melikyan… - Biochimica et Biophysica …, 1987 - Elsevier
A system of two planar bilayers holds a special place among the models employed for
investigating the mechanisms of membrane fusion. This is due to the fact that only this …

[图书][B] Introduction to biological membranes

MK Jain, RC Wagner - 1988 - core.ac.uk
The amount of information generated by intensive studies of biological membranes over the
past years is such that a comprehensive treatise is now a major undertaking. This new …