Tools and techniques for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)/COVID-19 detection

SH Safiabadi Tali, JJ LeBlanc, Z Sadiq… - Clinical microbiology …, 2021 - Am Soc Microbiol
SUMMARY The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute
respiratory disease coronavirus 2 (SARS-CoV-2), has led to millions of confirmed cases and …

SARS-CoV-2: structure, biology, and structure-based therapeutics development

MY Wang, R Zhao, LJ Gao, XF Gao… - Frontiers in cellular …, 2020 - frontiersin.org
The pandemic of the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
has been posing great threats to the world in many aspects. Effective therapeutic and …

[HTML][HTML] Characteristics of SARS-CoV-2 and COVID-19

B Hu, H Guo, P Zhou, ZL Shi - Nature reviews microbiology, 2021 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly transmissible
and pathogenic coronavirus that emerged in late 2019 and has caused a pandemic of acute …

High genetic barrier to SARS-CoV-2 polyclonal neutralizing antibody escape

F Schmidt, Y Weisblum, M Rutkowska, D Poston… - Nature, 2021 - nature.com
The number and variability of the neutralizing epitopes targeted by polyclonal antibodies in
individuals who are SARS-CoV-2 convalescent and vaccinated are key determinants of …

[HTML][HTML] Affinity maturation of SARS-CoV-2 neutralizing antibodies confers potency, breadth, and resilience to viral escape mutations

F Muecksch, Y Weisblum, CO Barnes, F Schmidt… - Immunity, 2021 - cell.com
Antibodies elicited by infection accumulate somatic mutations in germinal centers that can
increase affinity for cognate antigens. We analyzed 6 independent groups of clonally related …

From SARS and MERS to COVID-19: a brief summary and comparison of severe acute respiratory infections caused by three highly pathogenic human coronaviruses

Z Zhu, X Lian, X Su, W Wu, GA Marraro, Y Zeng - Respiratory research, 2020 - Springer
Within two decades, there have emerged three highly pathogenic and deadly human
coronaviruses, namely SARS-CoV, MERS-CoV and SARS-CoV-2. The economic burden …

[HTML][HTML] Role of favipiravir in the treatment of COVID-19

S Joshi, J Parkar, A Ansari, A Vora, D Talwar… - International Journal of …, 2021 - Elsevier
Abstract The coronavirus disease-2019 (COVID-19) outbreak all over the world has led the
researchers to strive to develop drugs or vaccines to prevent or halt the progression of this …

Comparative review of SARS-CoV-2, SARS-CoV, MERS-CoV, and influenza a respiratory viruses

Z Abdelrahman, M Li, X Wang - Frontiers in immunology, 2020 - frontiersin.org
The 2019 novel coronavirus (SARS-CoV-2) pandemic has caused a global health
emergency. The outbreak of this virus has raised a number of questions: What is SARS-CoV …

Coronavirus disease 2019 (COVID-19): patogenesis, manifestasi klinis dan pilihan terapi

Y Levani, AD Prastya… - Jurnal Kedokteran dan …, 2021 - jurnal.umj.ac.id
Abstract Coronavirus Disease 2019 (COVID-19) ditemukan pada akhir tahun 2019 tepatnya
bulan Desember di Kota Wuhan, Provinsi Huebei, China dan kemudian menyebar ke …

Lifting the mask on neurological manifestations of COVID-19

A Pezzini, A Padovani - Nature Reviews Neurology, 2020 - nature.com
As the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) epidemic spreads, it
is becoming increasingly evident that coronavirus disease 2019 (COVID-19) is not limited to …