Raynaud's phenomenon: from molecular pathogenesis to therapy

M Prete, MC Fatone, E Favoino, F Perosa - Autoimmunity reviews, 2014 - Elsevier
Raynaud's phenomenon (RP) is a well defined clinical syndrome characterized by recurrent
episodes of digital vasospasm triggered by exposure to physical/chemical or emotional …

Systemic lupus erythematosus and systemic sclerosis: all roads lead to platelets

M Scherlinger, V Guillotin, ME Truchetet… - Autoimmunity …, 2018 - Elsevier
Systemic lupus erythematosus (SLE) and systemic sclerosis (SSc) are two phenotypically
distincts inflammatory systemic diseases. However, SLE and SSc share pathogenic features …

Toll-like receptors in mediating pathogenesis in systemic sclerosis

L Frasca, R Lande - Clinical & Experimental Immunology, 2020 - academic.oup.com
Toll-like receptors (TLRs) are evolutionarily conserved receptors essential for the host
defence against pathogens. Both immune and non-immune cells can express TLRs …

Platelets in systemic sclerosis: the missing link connecting vasculopathy, autoimmunity, and fibrosis?

K Ntelis, D Bogdanos, T Dimitroulas, L Sakkas… - Current Rheumatology …, 2019 - Springer
Abstract Purpose of Review Platelets are no longer recognized solely as cell fragments
regulating hemostasis. They have pleiotropic functions and they are linked directly or …

[HTML][HTML] Respiratory syncytial virus infection is strongly correlated with decreased mean platelet volume

AA Renshaw, B Drago, N Toraya, EW Gould - International Journal of …, 2013 - Elsevier
Background To date, infections have usually been associated with elevations of the mean
platelet volume. We correlated infection with respiratory syncytial virus (RSV) with changes …

[HTML][HTML] Flow cytometric investigation of classical and alternative platelet activation markers

B Nagy Jr, IB Debreceni, J Kappelmayer - Ejifcc, 2013 - ncbi.nlm.nih.gov
Platelets show a substantial role in the maintenance of vascular integrity when these cells
after a rapid activation adhere to the vessel wall lesion, aggregate with other platelets and …

The contribution of platelets to the pathogenesis of Raynaud's phenomenon and systemic sclerosis

JD Pauling, VB O'Donnell, NJ Mchugh - Platelets, 2013 - Taylor & Francis
Raynaud's phenomenon (RP) describes the excessive vascular response of the digital
vessels in response to cold exposure and emotional stress. It is typically the earliest …

[HTML][HTML] Association of neutrophil extracellular trap levels with Raynaud's phenomenon, glomerulonephritis and disease index score in SLE patients from Brazil

ED Auer, VBB Hoch, EB da Silva, YR Zonta… - Immunobiology, 2024 - Elsevier
Neutrophil extracellular traps (NETs) are cell-extruded DNA strands coated with neutrophils'
nuclear proteins and enzymes from cytotoxic granules, produced by NETosis, a cell death …

The Association of Flow‐Mediated Dilatation and Blood Parameters in Primary Raynaud's Phenomenon

S Uzun, İ Kaya - International Journal of Clinical Practice, 2022 - Wiley Online Library
Introduction. Raynaud's phenomenon (RP) is a multifactorial disorder. If any underlying
disease cannot be determined to be responsible for RP, then it is considered to be the …

The role of mean platelet volume in the early detection of acute bronchiolitis: A prospective study

Ş Gökçe, Z Kurugöl, A Suner - The clinical respiratory journal, 2018 - Wiley Online Library
Introduction and objective Acute bronchiolitis might be associated with morbidity and
mortality in infants. The aim of this study was to evaluate the role of mean platelet volume …