Amyotrophic lateral sclerosis is a progressive adult-onset neurodegenerative disease that
primarily affects upper and lower motor neurons, but also frontotemporal and other regions …

Background To assess the worldwide variation of amyotrophic lateral sclerosis (ALS)
incidence, we performed a systematic review and meta-analysis of population-based data …

Introduction: Amyotrophic lateral sclerosis (ALS) is a rare neurological disorder
characterized by progressive deterioration of motor neurons. Assessment of the …

Background Understanding how prevalence, incidence, and mortality of motor neuron
diseases change over time and by location is crucial for understanding the causes of these …

Importance Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease;
understanding ALS risk factors is a critical public health issue. Objectives To evaluate the …

Alzheimer's disease and other idiopathic dementias are associated with epigenetic
transformations. These transformations connect the environment and genes to …

Up-to-date, accurate information on the disease burden of motor neuron disease (MND) is
the cornerstone for evidence-based resource allocation and healthcare planning. We aimed …

Abstract Problem/Condition: Amyotrophic lateral sclerosis (ALS), commonly known as Lou
Gehrig's disease, is a progressive and fatal neuromuscular disease for which no cure or …

Objective: To estimate the incidence of amyotrophic lateral sclerosis (ALS) in the United
States for calendar years 2014–2016 using data from the National ALS Registry (Registry) …

Objective: This review sought to gain a comprehensive, up-to-date understanding of the
epidemiology and cost and healthcare resource use (HCRU) burden of amyotrophic lateral …