Intestinal atresia and necrotizing enterocolitis: embryology and anatomy

S Sabbatini, N Ganji, S Chusilp, F Balsamo, B Li… - Seminars in Pediatric …, 2022 - Elsevier
The primitive gut originates at week 3 of gestation from the endoderm, with posterior
incorporation of the remaining embryo layers. Wnt, Notch and TLR4 pathways have been …

Intrauterine volvulus: systemic review of the literature with pooled analysis

T Acer-Demir, N Şahin-Uysal - Journal of Perinatology, 2024 - nature.com
Our objective is to analyse the observations related to intrauterine volvulus and assess how
clinical manifestations and treatment strategies impact prognosis. We conducted a …

Prenatal detection of chromosomal abnormalities and copy number variants in fetuses with congenital gastrointestinal obstruction

X Meng, L Jiang - BMC Pregnancy and Childbirth, 2022 - Springer
Background Congenital gastrointestinal obstruction (CGIO) mainly refers to the stenosis or
atresia of any part from the esophagus to the anus and is one of the most common surgical …

Duodenal atresia in 17q12 microdeletion including HNF1B: A new associated malformation in this syndrome

F Quintero‐Rivera, JS Woo… - American Journal of …, 2014 - Wiley Online Library
Deletions of chromosome 17q12 [OMIM 614527] encompass a wide range of phenotypes,
including renal cysts, diabetes mellitus, pancreatic structural abnormalities, genital tract …

Chromosomal abnormalities and pregnancy outcomes for fetuses with gastrointestinal tract obstructions

X Wu, L Su, Q Shen, Q Guo, Y Li, S Xu, N Lin… - Frontiers in …, 2022 - frontiersin.org
Fetal gastrointestinal tract obstruction (GITO) is the most frequently encountered
gastrointestinal defect in the prenatal period. This study aimed to investigate the genetic …

A Novel Use of Embryonic Gut Organoid Culture to Investigate Duodenal Atresia

MLM Jones, G Sarila, B O'Sullivan, S Haycock… - Journal of Pediatric …, 2024 - Elsevier
Background The cause of duodenal atresia (DA) is not known. Tandler's “solid cord”
hypothesis conflicts with current biological evidence. In humans, a genetic aetiology is …

Delayed development of vacuoles and recanalization in the duodenum: a study in human fetuses to understand susceptibility to duodenal atresia/stenosis

X Liu, Y Song, P Hao, X Chen, J Zhang… - Fetal and Pediatric …, 2022 - Taylor & Francis
Objective We compared the cross-sectional areas of the duodenum to the distal small
intestine during early gestation to determine if there is a difference in age for recanalization …

Considering the vascular hypothesis for the pathogenesis of small intestinal atresia: a case control study of genetic factors

T Gupta, W Yang, DM Iovannisci… - American Journal of …, 2013 - Wiley Online Library
Small intestinal atresia (SIA) is a rare congenital occlusion of the small intestine. SIA
development, particularly in the jejunum and ileum, has been associated with in utero …

The role of fibroblast growth factor 10 signaling in duodenal atresia

MLM Jones, G Sarila, P Chapuis, JM Hutson… - Frontiers in …, 2020 - frontiersin.org
Introduction Duodenal atresia (DA) is a congenital bowel obstruction requiring major surgery
in the first week of life. Three morphological phenotypes are described, reflecting increasing …

FGF10 and the mystery of duodenal atresia in humans

WJ Teague, MLM Jones, L Hawkey, IM Smyth… - Frontiers in …, 2018 - frontiersin.org
Background: Duodenal atresia (DA) is a congenital obstruction of the duodenum, which
affects 1 in 7000 pregnancies and requires major surgery in the 1st days of life. Three …