Stiff-person syndrome and related disorders—diagnosis, mechanisms and therapies
MC Dalakas - Nature Reviews Neurology, 2024 - nature.com
Stiff-person syndrome (SPS) is the prototypical and most common autoimmune neuronal
hyperexcitability disorder. It presents with stiffness in the limbs and axial muscles, stiff gait …
hyperexcitability disorder. It presents with stiffness in the limbs and axial muscles, stiff gait …
Epitope landscape in autoimmune neurological disease and beyond
Autoantibody binding has a central role in autoimmune diseases and has also been linked
to cancer, infections, and behavioral disorders. Autoimmune neurological diseases remain …
to cancer, infections, and behavioral disorders. Autoimmune neurological diseases remain …
Ten Years of Neurology® Neuroimmunology & Neuroinflammation Decade in Review
It has been a decade since the first issue of Neurology® Neuroimmunology &
Neuroinflammation (N2) launched in June 2014. In these 10 years, N2 has evolved to …
Neuroinflammation (N2) launched in June 2014. In these 10 years, N2 has evolved to …
Impaired Presynaptic Function Contributes Significantly to the Pathology of Glycine Receptor Autoantibodies
AL Wiessler, F Zheng, C Werner, M Habib… - Neurology …, 2025 - neurology.org
Background and Objectives Autoantibodies (aAbs) against glycine receptors (GlyRs) are
mainly associated with the rare neurologic diseases stiff person syndrome (SPS) and …
mainly associated with the rare neurologic diseases stiff person syndrome (SPS) and …
Curcumin analogue NL04 inhibits spinal cord central sensitization in rats with bone cancer pain by inhibiting NLRP3 inflammasome activation and reducing IL-1β …
L Chen, B Hua, Q He, Z Han, Y Wang, Y Chen… - European Journal of …, 2024 - Elsevier
The management and therapy of bone cancer pain (BCP) remain formidable clinical
challenges. Curcumin and its analogues have been shown to have anti-inflammatory and …
challenges. Curcumin and its analogues have been shown to have anti-inflammatory and …
Efficacy of apheresis in antibody‐negative progressive encephalomyelitis with rigidity and myoclonus
Y Aoki, M Sakata, H Suzuki, K Hori… - Therapeutic …, 2025 - Wiley Online Library
Introduction Progressive encephalomyelitis with rigidity and myoclonus (PERM) is
characterized by brainstem symptoms, muscle rigidity, and myoclonus. While autoantibodies …
characterized by brainstem symptoms, muscle rigidity, and myoclonus. While autoantibodies …
[HTML][HTML] Stiff-person syndrome
JF Baizabal-Carvallo - medlink.com
Stiff-person syndrome is a progressive neurologic disorder characterized by rigidity,
superimposed spasm, and abnormal postures and gait. In this article, the author discusses …
superimposed spasm, and abnormal postures and gait. In this article, the author discusses …