Simple Summary Within this review article the authors provide an unbiased review of the
oncolytic virus, reovirus, clinically formulated as pelareorep. In particular, the authors …

Bats are being increasingly recognized as reservoir hosts of highly pathogenic and zoonotic
emerging viruses (Marburg virus, Nipah virus, Hendra virus, Rabies virus, and …

Mammalian orthoreoviruses (reoviruses) are highly tractable experimental models for
studies of double-stranded (ds) RNA virus replication and pathogenesis. Reoviruses infect …

The quality of drinking water in the Netherlands has to comply with the Dutch Drinking Water
Directive: less than one infection in 10,000 persons per year may occur due to consumption …

Although reovirus infections are thought to be common in adults, there have been few
assessments of the seroprevalence of reovirus in young children. We developed an indirect …

Reovirus infections are initiated by the binding of viral attachment protein σ1 to receptors on
the surface of host cells. The σ1 protein is an elongated fiber comprised of an N-terminal tail …

Diverse families of viruses bind immunoglobulin superfamily (IgSF) proteins located in tight
junctions (TJs) and adherens junctions of epithelium and endothelium. However, little is …

In recent years novel human respiratory disease agents have been described in South East
Asia and Australia. The causative pathogens were classified as pteropine orthoreoviruses …

For many encephalitis cases, the cause remains unidentified. After 2 children (from the same
family) received a diagnosis of acute necrotizing encephalopathy at Centre Hospitalier …

Mammalian orthoreoviruses (MRVs) are known to cause mild enteric and respiratory
infections in humans. They are widespread and infect a broad spectrum of mammals. We …