Machine learning generalizability across healthcare settings: insights from multi-site COVID-19 screening

J Yang, AAS Soltan, DA Clifton - NPJ digital medicine, 2022 - nature.com
As patient health information is highly regulated due to privacy concerns, most machine
learning (ML)-based healthcare studies are unable to test on external patient cohorts …

Perspectives on validation of clinical predictive algorithms

AAH de Hond, VB Shah, IMJ Kant, B Van Calster… - NPJ Digital …, 2023 - nature.com
The generalizability of predictive algorithms is of key relevance to application in clinical
practice. We provide an overview of three types of generalizability, based on existing …

Diachronic and synchronic variation in the performance of adaptive machine learning systems: the ethical challenges

J Hatherley, R Sparrow - Journal of the American Medical …, 2023 - academic.oup.com
Objectives Machine learning (ML) has the potential to facilitate “continual learning” in
medicine, in which an ML system continues to evolve in response to exposure to new data …

Applications of machine learning on electronic health record data to combat antibiotic resistance

SE Blechman, ES Wright - The Journal of Infectious Diseases, 2024 - academic.oup.com
There is growing excitement about the clinical use of artificial intelligence and machine
learning technologies. Advancements in computing and the accessibility of machine …

Heterogeneity in Antidepressant Treatment and Major Depressive Disorder Outcomes Among Clinicians

S Rathnam, KL Hart, A Sharma, PF Verhaak… - JAMA …, 2024 - jamanetwork.com
Importance While abundant work has examined patient-level differences in antidepressant
treatment outcomes, little is known about the extent of clinician-level differences …

A simulation-based evaluation of machine learning models for clinical decision support: application and analysis using hospital readmission

VV Mišić, K Rajaram, E Gabel - NPJ Digital Medicine, 2021 - nature.com
The interest in applying machine learning in healthcare has grown rapidly in recent years.
Most predictive algorithms requiring pathway implementations are evaluated using metrics …

Machine learning based early mortality prediction in the emergency department

C Li, Z Zhang, Y Ren, H Nie, Y Lei, H Qiu, Z Xu… - International Journal of …, 2021 - Elsevier
Background It is a great challenge for emergency physicians to early detect the patient's
deterioration and prevent unexpected death through a large amount of clinical data, which …

COVID-19–associated coagulopathy: less fibrinolysis can be more harmful!

K Görlinger, JH Levy - Anesthesiology, 2021 - pubs.asahq.org
With more than 300,000 deaths, the United States is the country with the highest coronavirus
disease 2019 (COVID-19) death toll globally, and the hospitalization attributable to COVID …

Assessing optimal methods for transferring machine learning models to low-volume and imbalanced clinical datasets: experiences from predicting outcomes of Danish …

AS Millarch, A Bonde, M Bonde, KV Klein… - Frontiers in digital …, 2023 - frontiersin.org
Introduction Accurately predicting patient outcomes is crucial for improving healthcare
delivery, but large-scale risk prediction models are often developed and tested on specific …

PetBERT: automated ICD-11 syndromic disease coding for outbreak detection in first opinion veterinary electronic health records

S Farrell, C Appleton, PJM Noble, N Al Moubayed - Scientific Reports, 2023 - nature.com
Effective public health surveillance requires consistent monitoring of disease signals such
that researchers and decision-makers can react dynamically to changes in disease …