Diverse therapeutic developments for post-traumatic stress disorder (PTSD) indicate common mechanisms of memory modulation

SB Raut, PA Marathe, L van Eijk, R Eri… - Pharmacology & …, 2022 - Elsevier
Post-traumatic stress disorder (PTSD), characterized by abnormally persistent and
distressing memories, is a chronic debilitating condition in need of new treatment options …

[HTML][HTML] Alleviating anxiety and taming trauma: novel pharmacotherapeutics for anxiety disorders and posttraumatic stress disorder

N Singewald, SB Sartori, A Reif, A Holmes - Neuropharmacology, 2023 - Elsevier
Psychiatric disorders associated with psychological trauma, stress and anxiety are a highly
prevalent and increasing cause of morbidity worldwide. Current therapeutic approaches …

Brain-based biotypes of psychiatric vulnerability in the acute aftermath of trauma

JS Stevens, NG Harnett, LAM Lebois… - American journal of …, 2021 - Am Psychiatric Assoc
Objective: Major negative life events, such as trauma exposure, can play a key role in
igniting or exacerbating psychopathology. However, few disorders are diagnosed with …

Safety learning and the Pavlovian conditioned inhibition of fear in humans: Current state and future directions

PAF Laing, BJ Harrison - Neuroscience & Biobehavioral Reviews, 2021 - Elsevier
Safety learning occurs when an otherwise neutral stimulus comes to signal the absence of
threat, allowing organisms to use safety information to inhibit fear and anxiety in …

Aerobic exercise in the treatment of PTSD: an examination of preclinical and clinical laboratory findings, potential mechanisms, clinical implications, and future …

KM Crombie, TG Adams, JE Dunsmoor… - Journal of anxiety …, 2023 - Elsevier
Posttraumatic stress disorder (PTSD) is associated with heightened emotional responding,
avoidance of trauma related stimuli, and physical health concerns (eg, metabolic syndrome …

[HTML][HTML] Using chatbots for English language learning in higher education

N Annamalai, R Ab Rashid, UM Hashmi… - … and Education: Artificial …, 2023 - Elsevier
Despite the advancement of Chatbot technology, little is known about its affordances for
language learning, especially in the context of Malaysian higher education institutions …

Exercise-induced increases in Anandamide and BDNF during extinction consolidation contribute to reduced threat following reinstatement: Preliminary evidence from …

KM Crombie, A Sartin-Tarm, K Sellnow… - …, 2021 - Elsevier
Introduction We recently demonstrated that moderate-intensity aerobic exercise delivered
during the consolidation of fear extinction learning reduced threat expectancy during a test …

Translation of animal endocannabinoid models of PTSD mechanisms to humans: Where to next?

LJ Ney, KM Crombie, LM Mayo, KL Felmingham… - Neuroscience & …, 2022 - Elsevier
The endocannabinoid system is known to be involved in mechanisms relevant to PTSD
aetiology and maintenance, though this understanding is mostly based on animal models of …

Aerobic exercise and consolidation of fear extinction learning among women with posttraumatic stress disorder

KM Crombie, A Sartin-Tarm, K Sellnow… - … Research and Therapy, 2021 - Elsevier
This study tested whether aerobic exercise delivered during the consolidation window
following fear extinction learning reduces the return of fear among women with posttraumatic …

Renewal in human fear conditioning: A systematic review and meta-analysis

Y Wang, S Olsson, OV Lipp, LJ Ney - Neuroscience & Biobehavioral …, 2024 - Elsevier
Renewal is a 'return of fear'manipulation in human fear conditioning to investigate learning
processes underlying anxiety and trauma. Even though renewal paradigms are widely used …