Therapeutic inertia in the treatment of hyperglycaemia in patients with type 2 diabetes: a systematic review

K Khunti, MB Gomes, S Pocock… - Diabetes, Obesity …, 2018 - Wiley Online Library
Aims Therapeutic inertia, defined as the failure to initiate or intensify therapy in a timely
manner according to evidence‐based clinical guidelines, is a key reason for uncontrolled …

Combination therapy with an SGLT2 inhibitor as initial treatment for type 2 diabetes: a systematic review and meta-analysis

TY Milder, SL Stocker, C Abdel Shaheed… - Journal of clinical …, 2019 - mdpi.com
Background: Guidelines differ with regard to indications for initial combination
pharmacotherapy for type 2 diabetes. Aims: To compare the efficacy and safety of (i) sodium …

The Use of Rescue Insulin in the Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness Study (GRADE)

PA Hollander, H Krause-Steinrauf, NM Butera… - Diabetes …, 2024 - Am Diabetes Assoc
OBJECTIVE To describe rescue insulin use and associated factors in the Glycemia
Reduction Approaches in Diabetes: A Comparative Effectiveness Study (GRADE) …

Evaluation of the clinical and economic burden of poor glycemic control associated with therapeutic inertia in patients with type 2 diabetes in the United States

SN Ali, T Dang-Tan, WJ Valentine, BB Hansen - Advances in therapy, 2020 - Springer
Introduction Therapeutic inertia refers to the failure to initiate or intensify treatment in a timely
manner and is widespread in type 2 diabetes (T2D) despite the well-established importance …

Episodic real-time CGM use in adults with type 2 diabetes: results of a pilot randomized controlled trial

DA Price, Q Deng, M Kipnes, SE Beck - Diabetes Therapy, 2021 - Springer
Introduction Resistance to initiating insulin therapy is common for people with type 2
diabetes (T2D) using multiple oral agents, resulting in sustained poor glycemic control. We …

Changes in HbA1c and weight, and treatment persistence, over the 18 months following initiation of second-line therapy in patients with type 2 diabetes: results from …

J Wilding, T Godec, K Khunti, S Pocock, R Fox… - BMC medicine, 2018 - Springer
Background Intensification of metformin monotherapy with additional glucose-lowering
drugs is often required in patients with type 2 diabetes (T2D). This study evaluated changes …

Initiating therapy in patients newly diagnosed with type 2 diabetes: combination therapy vs a stepwise approach

E Cersosimo, EL Johnson… - Diabetes, Obesity and …, 2018 - Wiley Online Library
There is clear evidence that achieving glycaemic targets reduces the risk of developing
complications as a result of type 2 diabetes (T2D). Many patients, however, continue to have …

Assessing quality of care in pharmacy: remembering Donabedian

MT Rupp - Journal of managed care & specialty pharmacy, 2018 - jmcp.org
While some incremental and fragmented progress has been made in recent years,
assessing the quality of care provided by pharmacists and pharmacy organizations remains …

Oral semaglutide versus injectable glucagon-like peptide-1 receptor agonists: a cost of control analysis

BB Hansen, S Nuhoho, SN Ali, T Dang-Tan… - Journal of Medical …, 2020 - Taylor & Francis
Aims: The efficacy and safety of oral semaglutide, the first glucagon-like peptide-1 (GLP-1)
receptor agonist developed for oral administration for the treatment of type 2 diabetes, was …

A 96‐week, multinational, randomized, double‐blind, parallel‐group, clinical trial evaluating the safety and effectiveness of bexagliflozin as a monotherapy for adults …

YDC Halvorsen, GA Walford, J Massaro… - Diabetes, Obesity …, 2019 - Wiley Online Library
Aim To explore the safety and effectiveness of extended exposure to bexagliflozin as a
monotherapy for type 2 diabetes. Methods Adults with diabetes (n= 288) from the USA …