TFOS DEWS II definition and classification report

JP Craig, KK Nichols, EK Akpek, B Caffery, HS Dua… - The ocular …, 2017 - Elsevier
The goals of the TFOS DEWS II Definition and Classification Subcommittee were to create
an evidence-based definition and a contemporary classification system for dry eye disease …

Tfos dews ii epidemiology report

F Stapleton, M Alves, VY Bunya, I Jalbert, K Lekhanont… - The ocular …, 2017 - Elsevier
The subcommittee reviewed the prevalence, incidence, risk factors, natural history, morbidity
and questionnaires reported in epidemiological studies of dry eye disease (DED). A meta …

TFOS DEWS II diagnostic methodology report

JS Wolffsohn, R Arita, R Chalmers, A Djalilian… - The ocular …, 2017 - Elsevier
The role of the Tear Film and Ocular Surface Society (TFOS) Dry Eye Workshop (DEWS) II
Diagnostic Methodology Subcommittee was 1) to identify tests used to diagnose and monitor …

Tfos dews ii pathophysiology report

AJ Bron, CS de Paiva, SK Chauhan, S Bonini… - The ocular …, 2017 - Elsevier
Abstract The TFOS DEWS II Pathophysiology Subcommittee reviewed the mechanisms
involved in the initiation and perpetuation of dry eye disease. Its central mechanism is …

Tfos dews ii iatrogenic report

JAP Gomes, DT Azar, C Baudouin, N Efron… - The ocular …, 2017 - Elsevier
Dry eye can be caused by a variety of iatrogenic interventions. The increasing number of
patients looking for eye care or cosmetic procedures involving the eyes, together with a …

TFOS DEWS II sex, gender, and hormones report

DA Sullivan, EM Rocha, P Aragona, JA Clayton, J Ding… - The ocular …, 2017 - Elsevier
One of the most compelling features of dry eye disease (DED) is that it occurs more
frequently in women than men. In fact, the female sex is a significant risk factor for the …

[HTML][HTML] Inflammatory basis for dry eye disease flares

VL Perez, ME Stern, SC Pflugfelder - Experimental Eye Research, 2020 - Elsevier
Most patients with chronic dry eye disease (DED) have episodic flares, which can be
triggered by a variety of activities and environmental stresses. These flares are typically …

BCLA CLEAR-Contact lens complications

F Stapleton, M Bakkar, N Carnt, R Chalmers… - Contact Lens and …, 2021 - Elsevier
Contact lens-related complications are common, affecting around one third of wearers,
although most are mild and easily managed. Contact lenses have well-defined anatomical …

[HTML][HTML] Dry eye disease in the young: A narrative review

F Stapleton, FG Velez, C Lau, JS Wolffsohn - The ocular surface, 2024 - Elsevier
Dry eye disease (DED), a multifactorial ocular disease that significantly impacts quality of
life, is most commonly reported in adults. This review describes the prevalence, risk factors …

[HTML][HTML] A phase II randomized trial to evaluate the long-term (12-week) efficacy and safety of OC-01 (varenicline solution) nasal spray for dry eye disease: The …

H Quiroz-Mercado, E Hernandez-Quintela, KH Chiu… - The Ocular Surface, 2022 - Elsevier
Purpose Dry eye disease is characterized by loss of tear film stability. OC-01 (varenicline
solution) is a small-molecule nicotinic acetylcholine receptor agonist administered as a …