Biodiversity is defined as the presence of a variety of living organisms on the Earth that is
essential for human survival. However, anthropogenic activities are causing the sixth mass …

BACKGROUND Fertility in adult life may be severely impaired by gonadotoxic therapies. For
young boys who do not yet produce spermatozoa, cryopreservation of immature testicular …

BACKGROUND Childhood cancer incidence and survivorship are both on the rise.
However, many lifesaving treatments threaten the prepubertal testis. Cryopreservation of …

The stem cell field in veterinary medicine continues to evolve rapidly both experimentally
and clinically. Stem cells are most commonly used in clinical veterinary medicine in …

Medical treatments for cancers or other conditions can lead to permanent infertility. Infertility
is an insidious disease that impacts not only the ability to have a biological child but also the …

BACKGROUND Both pluripotent very small embryonic-like stem cells (VSELs) and induced
pluripotent stem (iPS) cells were reported in 2006. In 2012, a Nobel Prize was awarded for …

As gonadotoxic adverse effects of antineoplastic treatments can result in infertility, gamete
cryopreservation is routinely offered to patients as the strategy to preserve their fertility …

Research on in vitro spermatogenesis is important for elucidating the spermatogenic
mechanism. We previously developed an organ culture method which can support …

The ability to spur growth of early stage gametic cells recovered from neonates could lead to
significant advances in rescuing the genomes of rare genotypes or endangered species that …

Recovery of germ cells could be an option for preservation of the genetic pool of
endangered animals. In immature males, xenografting of testis tissue provides the …